99481-06-8

Upstream product

• 499-06-9 3,5-dimethylbenzoic acid 
• 27798-60-3 methyl 2-(2-methoxyphenyl)acetate 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 99481-07-9 5-(3,5-Dimethyl-benzoyl)-2-hydroxy-benzeneacetic acid 

Relevant academic research and scientific papers

Novel arylacetic acid derivatives

A compound having a potentially inhibitory effect on 15-hydroxy-prostaglandin dehydrognase (PGDH) and having the formula STR1 in which R1 and R2 are hydrogen or lower alkyl; R3 is hydrogen, lower alkyl or substituted or unsubstituted phenyl; R4, R5, and R6 are hydrogen, halogen, lower alkyl, lower alkoxy, cyano, carboxy or nitro; at least one of the groups R4 to R6 being hydrogen; R7 to R11 are hydrogen, halogen, cyano, lower alkyl, trifluoromethyl, lower alkoxy, hydroxy, lower acyl, lower alkoxycarbonyl, N,N,-diloweralkyl-aminocarbonyl or N,N-loweralkylene-aminocarbonyl; and R8 and R10 may in addition be carboxy; at least two of R7 to R11 always being hydrogen; and --A-- is --CO--, --CH2 --CO--, --CH=CH--, --CH=CH--CO-- or corresponding groups in which a hydrogen atom is replaced by a lower alkyl group. The invention comprises also lactones of those compounds in which R1 is hydrogen, and salts of those compounds which contain at least one carboxy group.