27798-60-3

Basic information

• Product Name: 2-METHOXYPHENYLACETIC ACID METHYL ESTER
• Synonyms: METHYL 2-METHOXYPHENYLACETATE;2-METHOXYPHENYLACETIC ACID METHYL ESTER;2-Methoxyphenylacetic acid methyl;2-Methoxybenzeneacetic acid methyl ester;Einecs 248-662-1;Methyl 2-(2-Methoxyphenyl)acetate;Benzeneacetic acid,2-Methoxy-, Methyl ester
• CAS NO: 27798-60-3
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• EINECS: 248-662-1
• Product Categories: Aromatic Esters
• Mol File: 27798-60-3.mol
• Article Data: 33

Chemical Properties

• Melting Point: 70.3-71.0 °C(Solv: ethanol, 41% (64-17-5))
• Boiling Point: 242.8°Cat760mmHg
• Flash Point: 94.8°C
• Appearance: /
• Density: 1.12
• Vapor Pressure: 0.0334mmHg at 25°C
• Refractive Index: 1.5160-1.5200
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-METHOXYPHENYLACETIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYPHENYLACETIC ACID METHYL ESTER(27798-60-3)
• EPA Substance Registry System: 2-METHOXYPHENYLACETIC ACID METHYL ESTER(27798-60-3)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 3272
• Hazardous Substances Data: 27798-60-3(Hazardous Substances Data)

Usage

Uses

2-Methoxyphenylacetic Acid Methyl Ester was used to obtain NMR spectral data for aromatics and phenylacetic acid derivatives.

InChI:InChI=1/C10H12O3/c1-12-9-6-4-3-5-8(9)7-10(11)13-2/h3-6H,7H2,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 93-25-4 2-methoxyphenylacetic acid 
• 67-56-1 methanol 
• 579-74-8 2-Methoxyacetophenone 
• 149-73-5 trimethyl orthoformate 
• 614-75-5 2-Hydroxyphenylacetic acid 
• 74-88-4 methyl iodide 
• 584-08-7 potassium carbonate 
• 201230-82-2 carbon monoxide 
• 612-16-8 (2-methoxyphenyl)methanol 
• 616-38-6 carbonic acid dimethyl ester 
• 6850-57-3 2-methoxybenzylamine 
• 6851-80-5 2-methoxy-N-methylbenzylamine 
• 22446-37-3 methyl (2-hydroxyphenyl)acetate 

Downstream Products

• 104174-90-5 1-(2-methoxy-phenyl)-2-methyl-propan-2-ol 
• 33390-80-6 2-(2-methoxyphenyl)acetamide 
• 54493-88-8 methyl 2-(2-methoxyphenyl)prop-2-enoate 
• 60779-19-3 Methyl (+/-)-2-(2-Methoxyphenyl)propanoate 
• 109217-20-1 [2-hydroxy-5-(2-thienylcarbonyl)phenyl]acetic acid 
• 104206-32-8 methyl α-<2-hydroxy-3-methoxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-yl>-2-methoxyphenylacetate 
• 133125-22-1 (2S,5S)-2-Benzyloxycarbonylamino-5-(2-methoxy-phenyl)-hexanedioic acid 1-tert-butyl ester 6-methyl ester 
• 133125-24-3 (2R,5S)-2-Benzyloxycarbonylamino-5-(2-methoxy-phenyl)-hexanedioic acid 1-tert-butyl ester 6-methyl ester 
• 5180-78-9 methyl 2-(2-methoxyphenyl)-2-oxoacetate 
• 167764-27-4 methyl [3-(2-bromopropionyl)-6-methoxyphenyl]acetate 
• 93-25-4 2-methoxyphenylacetic acid 
• 152955-17-4 methyl 2-(2-methoxyphenyl)-3-(2-O-methoxymethylphenyl)propanoate 
• 152955-20-9 methyl 2-(2-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 219660-45-4 1-(2-methoxyphenyl)penta-3,4-dien-2-one 

Relevant articles and documents

BISPHENOLATE TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF

Bis phenolate transition metal complexes are disclosed for use in alkene polymerization, with optional chain transfer agent, to produce polyolefins.

Dehydroxymethylation of alcohols enabled by cerium photocatalysis

Dehydroxymethylation, the direct conversion of alcohol feedstocks as alkyl synthons containing one less carbon atom, is an unconventional and underexplored strategy to exploit the ubiquity and robustness of alcohol materials. Under mild and redox-neutral reaction conditions, utilizing inexpensive cerium catalyst, the photocatalytic dehydroxymethylation platform has been furnished. Enabled by ligand-to-metal charge transfer catalysis, an alcohol functionality has been reliably transferred into nucleophilic radicals with the loss of one molecule of formaldehyde. Intriguingly, we found that the dehydroxymethylation process can be significantly promoted by the cerium catalyst, and the stabilization effect of the fragmented radicals also plays a significant role. This operationally simple protocol has enabled the direct utilization of primary alcohols as unconventional alkyl nucleophiles for radical-mediated 1,4-conjugate additions with Michael acceptors. A broad range of alcohols, from simple ethanol to complex nucleosides and steroids, have been successfully applied to this fragment coupling transformation. Furthermore, the modularity of this catalytic system has been demonstrated in diversified radical-mediated transformations including hydrogenation, amination, alkenylation, and oxidation.

A sustainable procedure toward alkyl arylacetates: Palladium-catalysed direct carbonylation of benzyl alcohols in organic carbonates

A sustainable procedure for the synthesis of various alkyl arylacetates from benzyl alcohols has been developed. With palladium as the catalyst and organic carbonates as the green solvent and in situ activator, benzyl alcohols were carbonylated in an efficient manner without any halogen additives.