99482-89-0Relevant academic research and scientific papers
Copper-catalyzed direct sulfenoamination of saturated ketones via in situ formed enaminones
Bi, Gehua,Bi, Yusong,Huang, Xin,Li, Chunyan,Wang, Jiateng,Yang, Kai,Zhang, Weimin,Zhao, Jie,Zhuang, Yunqing
, p. 1749 - 1753 (2022/03/02)
A sequential and efficient protocol for the synthesis of α-thiolated enaminones has been developed using copper-TEMPO systems. This reaction features a broad substrate scope to afford the desired product in good to excellent yields with high stereoselectivity. A preliminary mechanistic study suggests that the in situ formed enaminone acts as the key intermediate.
Synthesis of enaminones containing diverse N,N-disubstitution via simple transamination: a study with sustainable catalyst-free operation
Gao, Yong,Liu, Yunyun,Wei, Li,Wan, Jieping
, p. 5547 - 5555 (2017/09/23)
Abstract: A systematic investigation on the synthesis of β-enaminones containing diverse N,N-disubstitution via the transamination of N,N-dimethyl amino functionalized β-enaminones and secondary amines has been conducted by employing biomass available green solvent ethyl lactate as reaction medium. A class of β-enaminones containing different N,N-disubstitutions have been smoothly synthesized under the sustainable conditions without using any catalyst.
