99499-66-8

Upstream product

• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 99499-69-1 4-[(1R,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-1-yl]-butan-1-ol 
• 99499-68-0 [(1R,2S,6S)-6-(4-Benzyloxy-butyl)-7-oxa-bicyclo[4.1.0]hept-2-yloxy]-tert-butyl-dimethyl-silane 
• 99499-70-4 Toluene-4-sulfonic acid 4-[(1S,5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-1-yl]-butyl ester 
• 99499-71-5 Benzyl-{4-[(1S,5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-1-yl]-butyl}-amine 
• 99499-60-2 [3-(4-Benzyloxy-butyl)-cyclohex-2-enyloxy]-tert-butyl-dimethyl-silane 
• 99499-58-8 3-(4-benzyloxybutyl)cyclohex-2-enone 
• 99499-59-9 3-(4-Benzyloxy-butyl)-cyclohex-2-enol 
• 99499-65-7 (6S,7R,8R)-1-Benzyl-8-(tert-butyl-dimethyl-silanyloxy)-1-aza-spiro[5.5]undecan-7-ol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 99499-64-6 (6S,7R,8R)-1-Benzyl-8-(tert-butyl-dimethyl-silanyloxy)-7-iodo-1-aza-spiro[5.5]undecane 
• 109663-54-9 O-t-butyldimethylsilyl-N-benzyldepentylperhydrohistrionicotoxin 
• 83562-31-6 (6RS,7SR,8SR)-7-n-Butyl-N-benzyl-1-azaspiro<5.5>undecan-8-ol 
• 55228-77-8 (+/-)-depentylperhydrohistrionicotoxin 
• 99499-67-9 (6R,8S)-1-Benzyl-8-(tert-butyl-dimethyl-silanyloxy)-1-aza-spiro[5.5]undecane 

Relevant academic research and scientific papers

STEREOCONTROLLED SYNTHESIS OF THE HISTRIONICOTOXIN RING SYSTEM

Two simple, efficient and stereocontrolled routes to the cis-azaspiro--undecan-8-ol skeleton of the histrionicotoxin alkaloids are described.