995-14-2Relevant articles and documents
Ivanov et al.
, (1972)
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Ivanov,B.E.,Kudryavtseva,L.A.
, (1967)
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Synthesis and acid-base properties of α-aminophosphoryl compounds
Zakharov,Nuriazdanova,Garifzyanov,Galkin,Cherkasov
, p. 873 - 881 (2007/10/03)
α-Aminophosphoryl compounds of the phosphonate, phosphine oxide, and α,ω-bis(phosphine oxide) series and some of their thiophosphoryl analogs were synthesized. Potentiometric measurements of the pKa of the conjugate acids revealed an insignificant effect of variation of substituents on the phosphorus, nitrogen, and α-carbon atoms on the basicity of the phosphorylated amines. The latter are weak bases. Organophosphorus groups decrease the basicity of the amines by almost 5 pK a units. The role of the hydrophobic effect and intramolecular H-bonding in the obtained substances was discussed.
Reactions of aminals with amides and N-silylated amides of acids containing a three- or four-coordinate phosphorus atom
Pudovik, M.A.,Kibardina, L.K.,Terent'eva, S.A.,Pudovik, A.N.
, p. 2293 - 2297 (2007/10/02)
The reactions of 2-substituted 1,3,2-oxazaphospholidines and 1,3,2-dioxaphospholanes containing an endo- or exo-cyclic secondary amino group with aminals lead to the formation of dimers of cyclic phosphonimidates or phosphinimidates.The products of the reactions of acetylphosphoramidites and bis(trimethylsilyl)phosphoramidites with aminals and N-(alkoxymethyl)dialkylamines are dialkyl P-(aminomethyl)phosphonimidates.