99531-44-9

Upstream product

• 99531-47-2 Acetic acid (1S,2R,7R,9S,10S,11S)-2-acetoxymethyl-1,5-dimethyl-12-methylene-10-(tetrahydro-pyran-2-yloxy)-8-oxa-tricyclo[7.2.1.0^2,7]dodec-5-en-11-yl ester 
• 110-87-2 3,4-dihydro-2H-pyran 
• 77620-41-8 12-epi-3α-<(tetrahydropyranyl)oxy>-12,13-epoxytrichothec-9-ene-4β,15-diol 
• 99531-53-0 3α-<(tetrahydropyranyl)oxy>-10β-bromo-9α,15-epoxytrichothec-12-en-4β-ol 
• 99531-48-3 12,13-deoxyanguidine 
• 97337-72-9 12-epi-3α-<(tetrahydropyranyl)oxy>-10β-bromo-9α,15:12,13-diepoxytrichothecan-4β-ol 
• 2270-40-8 anguidine 
• 77620-40-7 C₂₄H₃₄O₈ 

Downstream Products

• 77620-41-8 12-epi-3α-<(tetrahydropyranyl)oxy>-12,13-epoxytrichothec-9-ene-4β,15-diol 
• 2270-40-8 anguidine 
• 77620-40-7 C₂₄H₃₄O₈ 

Relevant academic research and scientific papers

Trichothecene degradation studies. 2. Synthesis of [13-14C]anguidine

An efficient degradation and resynthesis of anguidine that pivots around norketone 4 is described. The sequence from anguidine to anguidine via 4 proceeds in 12 steps with an overall yield of 30%. This work has permitted for the first time the preparation of an enantiomerically pure, high specific activity 14C-labeled epoxytrichothecene mycotoxin required for biological investigations. The radiolabel was introduced by the reaction of 4 with [14C]CH2PPh3.