99539-57-8Relevant academic research and scientific papers
The synthesis of lactam analogues of fentanyl
Micovic, Ivan V.,Roglic, Goran M.,Ivanovic,Dosen-Micovic, Ljiljana,Kiricojevic, Vesna D.,Popovic, Jelena B.
, p. 2041 - 2050 (2007/10/03)
Fentanyl, sufentanil and alfentanil are clinically widely used anaesthetics and are structurally related to drugs with entirely different pharmacological activity such as droperidol, loperamide and lorcainide, etc. Therefore, in order to test their pharma
3-(1,3-dithiol-2-ylidene)-2,4-dioxopyrrolidines, -piperidines, and -hexahydroazepines and use thereof against hepatic diseases
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, (2008/06/13)
Novel thioketene derivatives of the formula: STR1 wherein R1 is hydrogen atom, an alkyl group, a lower alkenyl group, a phenyl group or a group of the formula: --B--Y; Y is a nitrogen-containing monocyclic heterocyclic group or a substituted or unsubstituted phenyl group; B is a straight or branched lower alkylene group; R2 and R3 are both a lower alkyl group or are combined together to form a group of the formula: --CH2 CH2 -- or --CH=CH--; R4 is hydrogen atom, a lower alkyl group or a (lower alkoxy)carbonyl group; A is a group of the formula: --(CH2)n -- or --CH(COOR5)--; n is an integer of 0, 1 or 2 and R5 is a lower alkyl group, are disclosed. The compound (I) is useful as an agent for treating and protecting various liver diseases.
