99539-69-2

Upstream product

• 156-60-5 trans-1,2-dichloroethylene 
• 29689-63-2 ethyl (N-benzylcarbamoyl)acetate 

Downstream Products

• 99539-70-5 ethyl 1-benzyl-5-(1,3-dithiol-2-ylidene)-4,6-dioxopiperidine-3-carboxylate 
• 99539-88-5 1-benzyl-5-(1,3-dithiol-2-ylidene)-4,6-dioxopiperidine-2,3-dicarboxylic acid diethyl ester 

Relevant academic research and scientific papers

3-(1,3-dithiol-2-ylidene)-2,4-dioxopyrrolidines, -piperidines, and -hexahydroazepines and use thereof against hepatic diseases

Novel thioketene derivatives of the formula: STR1 wherein R1 is hydrogen atom, an alkyl group, a lower alkenyl group, a phenyl group or a group of the formula: --B--Y; Y is a nitrogen-containing monocyclic heterocyclic group or a substituted or unsubstituted phenyl group; B is a straight or branched lower alkylene group; R2 and R3 are both a lower alkyl group or are combined together to form a group of the formula: --CH2 CH2 -- or --CH=CH--; R4 is hydrogen atom, a lower alkyl group or a (lower alkoxy)carbonyl group; A is a group of the formula: --(CH2)n -- or --CH(COOR5)--; n is an integer of 0, 1 or 2 and R5 is a lower alkyl group, are disclosed. The compound (I) is useful as an agent for treating and protecting various liver diseases.