99557-41-2Relevant academic research and scientific papers
Regioselective Ring Expansion of Isatins with in Situ Generated α-Aryldiazomethanes: Direct Access to Viridicatin Alkaloids
Tangella, Yellaiah,Manasa, Kesari Lakshmi,Krishna, Namballa Hari,Sridhar,Kamal, Ahmed,Nagendra Babu, Bathini
, p. 3639 - 3642 (2018)
A novel efficient one-pot regioselective ring-expansion reaction of isatins with in situ generated α-aryl/heteroaryldiazomethanes for the construction of viridicatin alkaloids has been described under metal-free conditions. The utility of this protocol is further demonstrated in the synthesis of naturally occurring viridicatin, viridicatol, and substituted 3-O-methyl viridicatin and their scale up.
