99563-85-6Relevant academic research and scientific papers
A one-pot esterification of chiral O-trimethylsilyl-cyanohydrins with retention of stereochemistry
Norsikian, Stephanie,Holmes, Ian,Lagasse, Franz,Kagan, Henri B
, p. 5715 - 5717 (2002)
Enantiomerically enriched O-TMS cyanohydrins have been transformed directly into O-acyl-cyanohydrins using various anhydrides or acid chlorides in the presence of catalytic amounts of scandium(III) triflate. The reaction occurs with full retention of ster
KINETIC RESOLUTION OF KETONE CYANOHYDRIN ACETATES WITH A MICROBIAL ENZYME
Ohta, Hiromichi,Kimura,Yoichi,Sugano, Yasushi
, p. 6957 - 6960 (2007/10/02)
Incubation of dl-1-cyano-1-metylalkyl (or alkenyl) acatates (methyl ketone cyanohydrin acetates) with cells of Pichia miso IAM 4682 afforded optically active acetates and the corresponding ketones via asymmetric hydrolysis.Resulting (S)-2-cyano-2-undecyl acetate was converted to the aminofuranone derivative without losing its optical purity.
NEW SYNTHETIC METHODS FOR 4-AMINO-2(5H)-FURANONES
Hiyama, Tamejiro,Oishi, Haruhito,Saimoto, Hiroyuki
, p. 2459 - 2462 (2007/10/02)
Two new efficient methods are disclosed for the synthesis of the title compounds: (1) base-promoted ring closure of 2-acyloxy alkanenitrile and (2) acid-mediated lactonization of t-butyl-4-alkoxy-3-amino-2-alkenoates.
