99564-56-4Relevant academic research and scientific papers
Direct amidation of carboxylic acids with tertiary amines: Amide formation over copper catalysts through C-N bond cleavage
Xiong, Biquan,Zhu, Longzhi,Feng, Xiaofeng,Lei, Jian,Chen, Tieqiao,Zhou, Yongbo,Han, Li-Biao,Au, Chak-Tong,Yin, Shuang-Feng
supporting information, p. 4244 - 4247 (2014/07/21)
A copper-catalyzed system for the amidation of carboxylic acids with tert-amines through C-N bond cleavage was developed. This protocol is practical and represents a simple way to produce functionalized amides from basic starting materials in moderate to good yields. A plausible mechanism is proposed for the reaction. Copyright
Indium-mediated microwave-assisted one-pot synthesis of α,β-unsaturated amides
Feng, Sunlin,Jiang, Shilei,Zhang, Zhiying,Yu, Xiaochun
experimental part, p. 392 - 394 (2010/11/18)
A stereoselective synthesis of α,β-unsaturated-N,N-diethyl amides was achieved by a one-pot reaction of triphenylphosphine, an aromatic aldehyde, and N,N-diethyl chloroacetamide in the presence of indium under microwave-assisted and solvent-free condition.
Synthesis of α β,-unsaturated amide via phosphonium ylide
Jiang, Shilei,Yang, Kefeng,Yu, Xiaochun
supporting information; experimental part, p. 1759 - 1767 (2009/11/30)
A series of ,-unsaturated amides were prepared by the Wittig reaction of N,N-diethylamidemethylenetriphenylphosphorane ylide with aldehydes with moderate to good yields. Copyright Taylor & Francis Group, LLC.
Microwave-assisted one-pot synthesis of α, β-unsaturated amides under solvent-free conditions
Jiang, Shilei,Xie, Yuanyuan,Yu, Xiaochun
experimental part, p. 24 - 26 (2009/10/02)
Under microwave-assisted solvent-free conditions a one-pot reaction of triphenylphosphine, an aldehyde and N, N-diethyl chloroacetamide in the presence of zinc dust affords α, β-unsaturated amides stereoselectively in good yield. In comparison with the co
A practical and efficient synthesis of (E)-β-aryl-α,β-unsaturated amides
Chen, Chih-Ching,Ho, Jung-Chieh,Chang, Nein-Chen
, p. 10350 - 10354 (2008/12/22)
In this paper, we report a one-step convergent synthesis of (E)-β-monosubstituted α,β-unsaturated amides 3 from α-sulfonyl acetamide 1 and benzyl bromide derivatives 2.
