99602-59-2

Upstream product

• 69366-55-8 benzyl 3-(3-methoxycarbonylpropyl)-2,4-dimethylpyrrole-5-carboxylate 
• 123-54-6 acetylacetone 
• 20194-18-7 sodium phenyl-methanolate 
• 99602-58-1 benzyl 3-(3-methoxycarbonylpropionyl)-2,4-dimethylpyrrole-5-carboxylate 
• 40236-19-9 benzyl 3,5-dimethylpyrrole-2-carboxylate 
• 2199-44-2 3,5-dimethyl-2-ethoxycarbonyl-1H-pyrrole 

Downstream Products

• 99602-65-0 benzyl 3-(3-methoxycarbonylpropyl)-4-methylpyrrole-2-carboxylate 
• 99602-64-9 benzyl 3-(3-benzyloxycarbonylpropyl)-4-methylpyrrole-2-carboxylate 
• 99602-60-5 benzyl 2-methoxycarbonyl-3-(3-methoxycarbonylpropyl)-4-methylpyrrole-5-carboxylate 

Relevant academic research and scientific papers

Biosynthesis of Porphyrins and Related Macrocycles. Part 25. Synthesis of Analogues of Coproporphyrinogen-III and Studies of their Interaction with Copropophyrinogen-III Oxidase from Euglena gracilis

Analogues of coproporphyrinogen-III have been synthesized in which the propionate groups respectively on ring-A and on ring-B are modified either by homologation or esterification.Coproporphyrinogen-III oxidase from Euglena gracilis acts on the analogues which possess normal substituents on ring-A to generate a vinyl group on that ring.The enzyme does not affect the analogues in which the ring-A propionate group has been changed.Conditions have been defined for the MacDonald synthesis of porphyrins which yield products of high isomeric purity.