99662-34-7

Basic information

• Product Name: 4-Pyrazol-1-yl-benzaldehyde
• Synonyms: 4-(1-PYRAZOLYL)BENZALDEHYDE;4-(1H-PYRAZOL-1-YL)BENZALDEHYDE;4-(1H-PYRAZOL-1-YL)BENZENECARBALDEHYDE;4-PYRAZOL-1-YL-BENZALDEHYDE;CHEMBRDG-BB 4004820;ASINEX-REAG BAS 08767263;TIMTEC-BB SBB010131;4-(1h-pyrazol-1-yl)benzaldehyde, 95+%
• CAS NO: 99662-34-7
• Molecular Formula: C₁₀H₈N₂O
• Molecular Weight: 172.18
• Product Categories: Carbonyl Compounds;Heterocycles
• Mol File: 99662-34-7.mol
• Article Data: 24

Chemical Properties

• Melting Point: 82-83°C
• Boiling Point: 310.1 °C at 760 mmHg
• Flash Point: 141.3 °C
• Appearance: /
• Density: 1.153 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.34±0.10(Predicted)
• CAS DataBase Reference: 4-Pyrazol-1-yl-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyrazol-1-yl-benzaldehyde(99662-34-7)
• EPA Substance Registry System: 4-Pyrazol-1-yl-benzaldehyde(99662-34-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 99662-34-7(Hazardous Substances Data)

Usage

General Description

4-Pyrazol-1-yl-benzaldehyde is a chemical compound that is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and advanced materials. It has a pyrazole ring attached to a benzaldehyde group, which gives it unique reactivity and properties. 4-Pyrazol-1-yl-benzaldehyde can be used as a building block for the preparation of heterocyclic compounds and is also known for its potential antimicrobial and anti-inflammatory properties. Additionally, 4-Pyrazol-1-yl-benzaldehyde may also serve as a valuable tool in the development of novel drugs and therapeutic agents due to its versatile chemical structure and reactivity. Overall, this chemical holds significance in the field of medicinal and chemical research due to its potential applications in drug discovery and material science.

InChI:InChI=1/C10H8N2O/c13-8-9-2-4-10(5-3-9)12-7-1-6-11-12/h1-8H

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 13788-92-6 1-(4-bromophenyl)-1H-pyrazole 
• 288-13-1 NH-pyrazole 
• 87199-17-5 4-formylphenylboronic acid, 
• 1122-91-4 4-bromo-benzaldehyde 
• 104-88-1 4-chlorobenzaldehyde 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 143426-47-5 4-pyrazol-1-yl-benzoic acid ethyl ester 
• 1194-02-1 4-fluorobenzonitrile 
• 25699-83-6 4-pyrazol-1-yl-benzonitrile 
• 459-57-4 4-fluorobenzaldehyde 
• 143426-49-7 1-(4-hydroxymethylphenyl)-1H-pyrazole 

Downstream Products

• 1187843-45-3 N-(1-(4-(1H-pyrazol-1-yl)phenyl)-2-(4-chlorophenethylamino)-2-oxoethyl)-4-fluorobenzamide 
• 1427505-27-8 adamantan-1-yl-(4-pyrazol-1-ylbenzyl)amine 

Relevant articles and documents

Two novel pyrazole-based chemosensors: "naked-eye" colorimetric recognition of Ni2+ and Al3+ in alcohol and aqueous DMF media

Two novel pyrazole-based chemosensors Pry-Flu and Pry-R6G were successfully synthesized, and their structures were confirmed by NMR spectroscopy and high-resolution mass spectroscopy (HRMS). The sensors Pry-Flu and Pry-R6G showed high selectivity and sens

HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention relates to a heterocyclic compound, a pharmaceutical composition comprising same, a preparation method therefor, and a use thereof. Specifically, the compound of the present invention is represented by formula (I), and used for preventing or treating a disease or condition related to RET activity.

BROAD SPECTRUM ANTIVIRAL COMPOSITIONS AND METHODS

Novel thiazole- and isoquinoline- containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-specturm viral infections are also presented. These compounds have shown inhibitio of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.