99662-34-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Pyrazol-1-yl-benzaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals for its unique reactivity and properties, contributing to the development of novel drugs and therapeutic agents.
Used in Agrochemical Industry:
4-Pyrazol-1-yl-benzaldehyde serves as an intermediate in the production of agrochemicals, leveraging its chemical structure to enhance the effectiveness of agricultural products.
Used in Advanced Materials:
4-Pyrazol-1-yl-benzaldehyde is utilized as a building block in the preparation of heterocyclic compounds, which are essential in creating advanced materials with specific properties for various applications.
Used in Antimicrobial Applications:
Due to its potential antimicrobial properties, 4-Pyrazol-1-yl-benzaldehyde is used as an active ingredient in antimicrobial formulations to combat microbial infections.
Used in Anti-inflammatory Applications:
Leveraging its anti-inflammatory potential, 4-Pyrazol-1-yl-benzaldehyde is applied in the development of anti-inflammatory agents to alleviate inflammation and related conditions.
Used in Research and Development:
4-Pyrazol-1-yl-benzaldehyde is used as a valuable tool in research and development for its versatile chemical structure, aiding in the discovery of new drugs and therapeutic agents.

InChI:InChI=1/C10H8N2O/c13-8-9-2-4-10(5-3-9)12-7-1-6-11-12/h1-8H

Upstream product

• 288-13-1 NH-pyrazole 
• 459-57-4 4-fluorobenzaldehyde 
• 25699-83-6 4-pyrazol-1-yl-benzonitrile 
• 1194-02-1 4-fluorobenzonitrile 
• 104-88-1 4-chlorobenzaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 
• 87199-17-5 4-formylphenylboronic acid, 
• 68-12-2 N,N-dimethyl-formamide 
• 13788-92-6 1-(4-bromophenyl)-1H-pyrazole 
• 143426-47-5 4-pyrazol-1-yl-benzoic acid ethyl ester 
• 143426-49-7 1-(4-hydroxymethylphenyl)-1H-pyrazole 
• 451-46-7 4-fluorobenzoic acid ethyl ester 

Downstream Products

• 143426-69-1 ethyl 4-(1H-pyrazol-1-yl)propenoate 
• 179055-56-2 Cycloheptyl-(4-pyrazol-1-yl-benzyl)-amine 
• 545424-10-0 (2E)-3-[4-(1H-Pyrazol-1-yl)phenyl]-2-propenal 
• 1043508-17-3 C₂₁H₂₁ClN₄O 
• 942950-51-8 4-((4-(2-(4-(1H-Pyrazol-1-yl)phenyl)-6-bromo-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-2-methylthiazole 
• 1202553-17-0 C₁₈H₁₆N₄ 
• 1177251-58-9 1-{(1-benzyl-1H-tetrazol-5-yl)[4-(1H-pyrazol-1-yl)phenyl]methyl}-4-cyclobutyl-1,4-diazepane 
• 1333472-32-4 potassium 2-(4-(1H-pyrazol-1-yl)phenyl)-2-methoxyacetate 
• 1333471-27-4 2-(4-(1H-pyrazol-1-yl)phenyl)-1-(4-(4-bromo-3,5-dimethoxyphenyl)thiazol-2-yl)-2-methoxyethanone 
• 1333472-35-7 2-(4-(1H-pyrazol-1-yl)phenyl)-N,2-dimethoxy-N-methylacetamide 
• 1333472-34-6 2-(4-(1H-pyrazol-1-yl)phenyl)-2-methoxyacetic acid 
• 1207549-69-6 (E)-2-{4-(1H-pyrazol-1-yl)phenyl}-N'-(4-bromo-3,5-dimethoxybenzylidene)-2-methoxyacetohydrazide 
• 1207550-04-6 C₂₂H₂₃BrN₄O₄ 
• 1207550-06-8 C₂₃H₂₅BrN₄O₄ 

Relevant academic research and scientific papers

Two novel pyrazole-based chemosensors: "naked-eye" colorimetric recognition of Ni2+ and Al3+ in alcohol and aqueous DMF media

Two novel pyrazole-based chemosensors Pry-Flu and Pry-R6G were successfully synthesized, and their structures were confirmed by NMR spectroscopy and high-resolution mass spectroscopy (HRMS). The sensors Pry-Flu and Pry-R6G showed high selectivity and sens

Attaching azoles to Hantzsch 1,4-dihydropyridines: Synthesis, theoretical investigation of nonlinear optical properties, antimicrobial evaluation and molecular docking studies

In the present study, we designed three novel compounds via the combination of two precious nitrogen-containing scaffolds; 1,4-dihydropyridine (DHP) and azole, in the same molecule. To synthesize the title compounds, initially, azolyl benzaldehydes were o

HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention relates to a heterocyclic compound, a pharmaceutical composition comprising same, a preparation method therefor, and a use thereof. Specifically, the compound of the present invention is represented by formula (I), and used for preventing or treating a disease or condition related to RET activity.

A highly selective colorimetric fluorescent probe for detection of Hg2+ and its application on test strips

An efficient fluorescent probe Pyr-Rhy based on pyrazole was developed, which can detect Hg2+ in water. Its fluorescence properties were studied by UV-vis and fluorescence spectroscopy, and the study results indicated that this probe can select

BROAD SPECTRUM ANTIVIRAL COMPOSITIONS AND METHODS

Novel thiazole- and isoquinoline- containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-specturm viral infections are also presented. These compounds have shown inhibitio of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.

Design and Synthesis of 2-Substitutedphenyl Benzo[D]Thiazole Derivatives and Their β-Amyloid Aggregation and Cholinesterase Inhibitory Activities

The occurrence of amyloid-β (Aβ) and reduced cholinergic tranmission are two major hallmarks of Alzheimer’s disease (AD). Therefore, a series of new 2-phenylbenzo[d]thiazoles substituted with azole/piperazine moieties were designed, synthesized, and evaluated as potential dual inhibitors of Aβ aggregation and cholinesterase (ChE) activities. In vitro studies showed that compound 2m containing an imidazole ring strongly inhibited Aβ1–40 (49.2%) and Aβ1-42 aggregation (60.6%). All derivatives exhibited weak inhibitory activities against both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Therefore, compound 2m may represent promising therapeutic option for inhibiting Aβ-mediated pathology in AD.

SUBSTITUTED AZACYCLES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describe

Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem-Difluoroalkenes

A novel strategy for the expedient construction of CF3-embeded tertiary/quarternary carbon centers was developed by taking advantage of photoredox catalysis. Thanks to a key step of single-electron oxidation, electron-rich gem-difluoroalkenes, which otherwise are essentially reluctant towards F-nucleoplilic addition, now readily participate in this fluoroallylation reaction. Furthermore, this strategy provides an elegant example for the generation, as well as functionalization, of α-CF3-substituted benzylic radical intermediates using cheap and readily available starting materials.

MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition and the use of compound formula (I).

Combined reactor and method of preparing pyrazolyl benzaldehyde acetal p-phenylene diamine bis-schiff base by using combined reactor

The invention relates to a combined reactor and a method of preparing pyrazolyl benzaldehyde acetal p-phenylene diamine bis-schiff base by using the combined reactor. The reactor mainly comprises a heating magnetic stirrer and a mating reaction device, wh