143426-49-7

Basic information

• Product Name: (4-Pyrazol-1-ylphenyl)methanol
• Synonyms: (4-PYRAZOL-1-YL-PHENYL)METHANOL;4-(1-PYRAZOLYL)BENZYLALCOHOL;[4-(1H-PYRAZOL-1-YL)PHENYL]METHANOL;BUTTPARK 98\50-44;RARECHEM AL BD 1319;4-Pyrazol-1-ylbenzyl alcohol;(4-PYRAZOL-1-YL-PHENYL)METHANOL 95%;4-(1H-Pyrazol-1-yl)benzyl alcohol
• CAS NO: 143426-49-7
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Product Categories: Alcohols and Derivatives;Heterocycles;Pyrazole series
• Mol File: 143426-49-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 76-80°C
• Boiling Point: 324.259 °C at 760 mmHg
• Flash Point: 149.907 °C
• Appearance: /
• Density: 1.167 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.25±0.10(Predicted)
• CAS DataBase Reference: (4-Pyrazol-1-ylphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Pyrazol-1-ylphenyl)methanol(143426-49-7)
• EPA Substance Registry System: (4-Pyrazol-1-ylphenyl)methanol(143426-49-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 143426-49-7(Hazardous Substances Data)

Usage

General Description

(4-Pyrazol-1-ylphenyl)methanol, also known as 4-Pyrazolylphenylmethanol, is a chemical compound with the molecular formula C10H10N2O. It is a white to off-white solid that is sometimes used as a building block in the synthesis of pharmaceutical compounds and other organic compounds. This chemical is a pyrazole derivative, which makes it useful in the development of various pharmaceutical drugs. It can also be used as a reagent in organic synthesis for the formation of carbon-carbon and carbon-nitrogen bonds. Additionally, it has potential applications in the fields of medicinal chemistry and agrochemicals. Overall, (4-Pyrazol-1-ylphenyl)methanol plays a significant role as an intermediate in the production of various organic and pharmaceutical compounds.

InChI:InChI=1/C10H10N2O/c13-8-9-2-4-10(5-3-9)12-7-1-6-11-12/h1-7,13H,8H2

Upstream product

• 99662-34-7 4-(1H-pyrazol-1-yl)benzaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 
• 619-44-3 methyl 4-iodobenzoate 
• 400750-29-0 methyl 4-(1H-pyrazol-1-yI)benzenecarboxylate 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 143426-47-5 4-pyrazol-1-yl-benzoic acid ethyl ester 

Downstream Products

• 1187450-65-2 tert-butyl (tert-butoxycarbonyl(6-((4-(pyrazol-1-yl)benzyl)(pyridin-3-ylsulfonyl)aminomethyl)pyridin-2-yl)amino)acetate 
• 1174064-63-1 4-(4-bromo-1H-pyrazol-1-yl)benzaldehyde 
• 1187451-41-7 (6-((4-(pyrazol-1-yl)benzyl)(pyridin-3-ylsulfonyl)aminomethyl)pyridin-2-ylamino)acetic acid 
• 1187451-19-9 isopropyl 2-{[6-({N-[4-(1H-pyrazol-1-yl)benzyl]pyridine-3-sulfonamido}methyl)pyridin-2-yl]amino}acetate 

Relevant articles and documents

HETEROAROMATIC COMPOUNDS AND USES THEREOF

Providing heteraromatic compounds and uses thereof. In particular, providing heteraromatic compounds of formula (I), pharmaceutical compositions comprising same, methods for preparing same and uses thereof, wherein the variables are as defined in the description.

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition and the use of compound formula (I).