99701-26-5

Upstream product

• 15136-32-0 (N-(tert-butoxycarbonyl)-L-leucinyl)-L-phenylalanine methyl ester 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 99701-53-8 (S)-2-{(S)-2-[((S)-2-tert-Butoxycarbonylamino-N-hydroxy-4-methyl-pentanimidoyl)-amino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methyl ester 
• 99701-36-7 [(S)-1-(5-Benzyl-6-oxo-5,6-dihydro-4H-[1,2,4]oxadiazin-3-yl)-3-methyl-butyl]-carbamic acid tert-butyl ester 
• 99701-37-8 [(S)-1-(5-Benzyl-6-oxo-1,4,5,6-tetrahydro-[1,2,4]triazin-3-yl)-3-methyl-butyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Novel approaches to optically active substituted 4,5-dihydro-1,2,4-triazin-6(1H)-ones as conformationally constrained peptidomimetics

Synthesis of 4,5-dihydro-1,2,4-triazin-6-ones bearing different chiral α-amino acid residues at the C3 and N1 positions is reported. Cyclocondensation of N-thioacylphthalimides with α-amino hydrazides afforded C3 functionalised dihydrotriazinones in good

In Situ Reagent for Thionation of Amides, Peptides and Lactams

An in situ reagent 1A for thionation of amides, peptides and lactams is prepared from phosphorus decasulfide/sodium carbonate (1:1 ratio) in THF at 25 deg C.