99702-43-9

Upstream product

• 99822-20-5 4,5-dihydro-5-phenyl-1,2,4-triazine-6(1H)-one 
• 99822-22-7 (Dimethylamino-methyleneamino)-phenyl-acetic acid methyl ester 
• 143668-50-2 Amino-phenyl-acetic acid hydrazide 

Downstream Products

• 119017-47-9 6-Methoxy-5-phenyl-[1,2,4]triazine 
• 99702-55-3 6-(benzylsulfonyl)-5-phenyl-1,2,4-triazine 
• 99702-52-0 6-(benzylsulfinyl)-5-phenyl-1,2,4-triazine 
• 99702-49-5 6-(benzylthio)-5-phenyl-1,2,4-triazine 
• 123346-82-7 7-Methoxy-2,6-diphenyl-pyrrolo[3,4-c]pyridine-1,3-dione 
• 119017-46-8 6-Chloro-5-phenyl-[1,2,4]triazine 
• 99702-46-2 5-phenyl-1,2,4-triazine-6-thione 

Relevant academic research and scientific papers

Synthesis of 1,2,4-Triazines, XV. - Synthesis of 1,2,4-Triazin-6(1H)-ones

1,2,4-Triazin-6(1H)-ones 3 have been prepared by cyclization of α-ketoacyl chlorides 15 with amidrazones 14. 4,5-Dihydro-1,2,4-triazin-6(1H)-ones 5 were obtained by cyclization of amino acid hydrazides 10 with orthocarboxylates 11.Key Word: 1,2,4-Triazin-

Reaction of 1,2,4-Triazines with N-Phenylmaleimide

Diels-Alder addition of N-phenylmaleimide (2) to 1,2,4-triazines (1) occurded across carbons 3 and 6 of the triazines to give 1:1 adducts.After losing nitrogen, they gave dihydropyridines, which underwent a variety of further reactions.Pyridine derivative

Efficient Synthesis of 5-Substituted-4,5-dihydro-1,2,4-triazin-6-ones and 5-Substituted-1,2,4-triazin-6-ones

Treatment of methyl α-(dimethylaminomethyleneamino)carboxylates 1 (from α-amino acids and dimethylformamide dimethylacetal) with hydrazine gives 5-substituted-4,5-dihydro-1,2,4-triazin-6-ones 2, which are smoothly dehydrogenated to 5-substituted-1,2,4-tri