99735-43-0

Usage

Uses

Used in Pharmaceutical Industry:
(1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID is used as a potential antidepressant and anxiolytic for its ability to modulate 5-HT1A and 5-HT1B serotonin receptors, which are important targets for medications used to treat mood disorders and anxiety.
Used in Substance Abuse Treatment:
(1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID is used as a potential treatment for substance abuse disorders due to its investigation for this purpose, although more research is needed to fully understand its pharmacological effects and potential therapeutic applications.

InChI:InChI=1/C13H15NO3/c1-9(10-5-3-2-4-6-10)14-8-11(13(16)17)7-12(14)15/h2-6,9,11H,7-8H2,1H3,(H,16,17)/p-1/t9-,11-/m1/s1

Upstream product

• 97-65-4 2-methylenesuccinic acid 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 99735-45-2 methyl (3R)-1-<(R)-1-phenylethyl>-5-oxo-3-pyrrolidinecarboxylate 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 617-52-7 Dimethyl itakonate 
• 915302-94-2 (3RS)-1-<(R)-1-phenylethyl>-5-oxo-3-pyrrolidinecarboxylic acid 

Downstream Products

• 269407-03-6 (R)-N-methoxy-N-methyl-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxamide 
• 1421341-21-0 C₃₂H₃₄N₂O₅ 
• 1421341-20-9 C₂₉H₂₈N₂O₂ 
• 1421339-71-0 (R)-4-((R)-1-(7-(3,4,5-trimethoxyphenyl)quinolin-5-yloxy)ethyl)pyrrolidin-2-one 
• 1421339-70-9 (R)-4-((R)-1-(7-phenylquinolin-5-yloxy)ethyl)pyrrolidin-2-one 
• 1319736-51-0 (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one 
• 1319736-58-7 (4R)-4-((R)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one 
• 1319736-57-6 (R)-N-methoxy-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxamide 
• 1165450-70-3 (R)-4-(hydroxymethyl)pyrrolidine-2-one 
• 1319738-12-9 (R)-4-[7-(3-Fluoro-4-isopropoxy-phenyl)-[1,6]naphthyridine-5-yloxy-methyl]-pyrrolidine-2-one 
• 1319738-10-7 (R)-4-((7-(3,4-dimethoxyphenyl)-1,6-naphthyridine-5-yloxy)methyl)pyrrolidine-2-one 
• 1319738-03-8 (R)-4-{7-[3-methoxy-4-(tetrahydro-pyran-4-yloxy)phenyl]-[1,6]naphthyridine-5-yloxymethyl}pyrrolidine-2-one 
• 1319737-92-2 (R)-4-((7-(4-hydroxy-3-methoxyphenyl)-1,6-naphthyridine-5-yloxy)methyl)pyrrolidine-2-one 
• 1319738-00-5 (S)-4-((7-(3,4,5-trimethoxyphenyl)-1,6-naphthyridine-5-ylamino)methyl)pyrrolidine-2-one 

Relevant academic research and scientific papers

AMIDE COMPOUND

The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. In the formula (I), each symbol is as defined in the specification.

Adamantyl Iminocarbonyl-Substituted Pyrimidines As Inhibitors Of 11-Beta-HSD1 826

A compound of formula (I): and pharmaceutically-acceptable salts thereof, wherein the variable groups are defined within; their use in the inhibition of 11βHSD1, processes for making them and pharmaceutical compositions comprising them are also described

SPIRO CONDENSED PIPERIDNES AS MODULATORS OF MUSCARINIC RECEPTORS

The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

BENZOIC ACID COMPOUNDS AND USE THEREOF AS MEDICAMENTS

Benzoic acid compounds of the formula STR1 wherein each symbol is as defined in the specification, optical isomers thereof and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising this compound and pharmaceutically acceptable additive; and serotonin 4 receptor agonists, gastrointestinal prokinetic agents and therapeutic agents for various gastrointestinal diseases, which comprise this compound as active ingredient. The compounds of the present invention have high and selective affinity for serotonin 4 receptor, and show agonistic effects thereon. Accordingly, they are useful medications for the prophylaxis and treatment of various gastrointestinal diseases, central nervous disorders, cardiac function disorders, urinary diseases, and the like, as well as useful anti-nociceptors for analgesic use which increase threshold of pain.