99747-54-3

Usage

Molecular structure

A complex structure with a pyrimidine-2,4-dione core, a 1,3-dimethyl substituent, a phosphoranylideneamino group, and a triphenylphosphoranylidene group.

Core component

Pyrimidine-2,4-dione, which is a heterocyclic compound with two carbonyl groups at positions 2 and 4.

1,3-Dimethyl

Two methyl groups attached to the first and third carbon atoms of the pyrimidine ring.

Phosphoranylideneamino group

A phosphorus-containing group with a double bond to the nitrogen atom of the pyrimidine ring.

Triphenylphosphoranylidene group

A phosphorus-containing group with three phenyl rings attached to the phosphorus atom.

Potential applications

Possible uses in pharmaceuticals or as a chemical reagent due to its unique structure and properties.

Research status

Further research is needed to fully understand its potential applications and effects.

Chemical classification

A heterocyclic compound with a combination of nitrogen, carbon, and phosphorus atoms.

Functional groups

Contains carbonyl groups, methyl groups, and phosphorus-containing groups.

Structural features

The presence of a phosphorus atom with a double bond to the nitrogen atom and three phenyl rings attached to the phosphorus atom.

Chemical reactivity

The compound may exhibit reactivity due to the presence of various functional groups and the phosphorus atom.

Stability

The stability of the compound may depend on factors such as temperature, pH, and the presence of other chemicals or reagents. Further research is needed to determine its stability under different conditions.

Upstream product

• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 2526-64-9 dichlorotriphenylphosphorane 
• 61541-41-1 6-azido-1,3-dimethylpyrimidine-2,4(1H,3H)-dione 
• 603-35-0 triphenylphosphine 
• 1560-54-9 allyltriphenylphosphonium bromide 

Downstream Products

• 137320-23-1 6-<(4-Chlorophenyl)imino>-2,4-dimethylpyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 137320-21-9 6-<(4-Nitrophenyl)imino>-2,4-dimethylpyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 137320-22-0 6-<<(4-Methylphenyl)sulfonyl>imino>-2,4-dimethylpyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 137320-18-4 2,4-Dimethyl-6-(phenylimino)pyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 137320-24-2 2,4,10-Trimethyl-6-(phenylimino)pyrido<1',2':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 152897-86-4 6-<(4-Chlorophenyl)amino>-2,4-dimethyl-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 152897-85-3 2,4-Dimethyl-6-(phenylamino)-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 152897-88-6 6-<(4-Methylphenyl)amino>-2,4-dimethyl-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 
• 152897-87-5 6-<<3-(Trifluoromethyl)phenyl>amino>-2,4-dimethyl-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione 

Relevant academic research and scientific papers

A facile synthesis of pyrrolo-[3,2-d]pyrimidines from 6-azidouracils and ylide phosphoranes

A series of the title compounds, 9-deazaxanthines, was regioselectively prepared in reasonable yields as major products from the reactions of 6-azidouracils 1a,b with stabilized ester-2a,b or keto-2c ylide phosphoranes and a moderated phosphorus ylide 3, instead of the expected triazoles. Side products were also observed wherein pyrimido[5,4-g]pteridine-2,4,5,7-tetrone (15) and other fused ring systems or acyclic-substituted uracil derivatives were isolated. A comparative study on the reactivity of 1a in analogy to 1b toward phosphoranes is also described.

Pyrido[2,3-d]pyrimidines, II [1]. One Step Synthesis of Pyrido[2,3-d]pyrimidines and Pyrimido[4,5-b]quinolines from 6-Amino Uracils

Reduction of 6-azidouracils 2 with hydrogen palladium or sodium dithionite afforded the corresponding 6-aminouracils 5 which could also be obtained by reaction of 2 with triphenylphosphane via phosphazenes and subsequent hydrolysis (Staudinger reaction). The use of trimethylphosphite instead of phosphanes yields with 2b the expected trimethoxyphosphazene 3c, whereas 2a reacts to the phosphonoaminopyrimidine 4. The syntheses of 5-hydroxy pyrido[2,3-d]pryimidine-2,4,7-triones 6, pyrido[2,3-d]pyrimidine-2,4,5-triones 8, cyclopenta[e]pyrido[2,3-d]pyrimidin-2,4,5-triones 7a, c, and tetrahydro-pyrimido[4,5-b]quinolin-2,4,5-triones 7b, d by condensation of 6-aminouracils 5 with malonates, ethylaceto/benzoylacetate, ethyl 2-oxocyclopentanecarboxylate and ethyl 2-oxocyclohexanecarboxylate, respectively, are described.

Reactions of Uracils. 6. New Ring Transformations of 6-Aminouracils with Acetylenedicarboxylates to Pyridinedionates and Pyrrolopyridines. Some Revised Constitutions

Treatment of 6--1,3-dimethyluracils 8 with dialkyl acetylenedicarboxylates in aprotic solvents affords zwitterionic pyridinedionates 12, involving a novel ring transformation reaction, via cleaving attack of a terminal carbanion to the 2-carbonyl of the uracil.In protic solvents 12 undergo a smooth heterocyclization reaction to give the pyrrolopyridines 14.The structures of 12b and 14b have been established by single-crystal X-ray diffraction.By spectroscopic comparison as well as by independent syntheses 12 proved to be closely related (phosphorylated) analogues of previously reported "ureas 17 and 18", while 13 was identical with the "5-propynoyluracil 15".Catalytic hydrogenation of 13a gave carbinol 20, which proved by means of 1H (H-D exchange) and 13C NMR to be identical with "cis-olefin 19".