99793-10-9

Usage

Uses

Used in Organic Synthesis:
Z-L-aspartic acid β-allyl ester is used as a building block for the creation of complex molecules due to its functional β-allyl ester group containing a double bond.
Used in Pharmaceutical Industry:
Z-L-aspartic acid β-allyl ester is used as a precursor for the synthesis of various drugs and pharmaceutical compounds, contributing to the development of new medications.
Used in Antimicrobial Applications:
Z-L-aspartic acid β-allyl ester is studied for its potential antimicrobial properties, which could be utilized in the development of new antibiotics or antimicrobial agents.
Used in Anticancer Applications:
Z-L-aspartic acid β-allyl ester is studied for its potential anticancer properties, indicating its possible use in the development of new cancer treatments or therapies.

Upstream product

• 127949-86-4 N-benzyloxycarbonyl-L-asparatic acid diallyl ester 
• 1152-61-0 N-Cbz-L-Asp 
• 47307-26-6 (S)-2-benzyloxycarbonylamino-succinic acid 1-tert-butyl ester 
• 123975-50-8 (S)-N-benzyloxycarbonylaspartic acid α-tert-butyl β-allyl ester 
• 31139-36-3 dibenzyl dicarbonate 
• 123975-49-5 (S)-4-(allyloxy)-2-amino-4-oxobutanoic acid hydrochloride 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 123975-50-8 (S)-N-benzyloxycarbonylaspartic acid α-tert-butyl β-allyl ester 
• 1154041-24-3 C₂₅H₂₈N₂O₇ 
• 127605-40-7 (3E,2S)-2-benzyloxycarbonylamino-4-phenyl-3-butenoic acid tert-butyl ester 
• 127605-41-8 (3Z,2S)-2-benzyloxycarbonylamino-4-phenyl-3-butenoic acid tert-butyl ester 
• 127605-39-4 2-oxo-3-(1-t-butyloxycarbonyl-1-benzyloxycarbonylamino-(S)-methyl)-4-ethyl-oxetane 
• 127605-42-9 t-butyl 2-benzyloxycarbonylamino-(S,Z)-3-hexenoate 
• 123975-51-9 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-hydroxy-4-phenyl-(2S)-butanoate 
• 123975-56-4 (2S)-3-allyloxycarbonyl-2-benzyloxycarbonylamino-4-hydroxy-4-phenyl-butanoic acid tert-butyl ester 
• 123975-58-6 (2S)-2-benzyloxycarbonylamino-3-carboxy-4-hydroxy-4-phenyl-butanoic acid tert-butyl ester 
• 123975-57-5 t-butyl 2-benzyloxycarbonylamino-3-allyloxycarbonyl-4-hydroxy-(2S)-hexanoate 
• 123999-77-9 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-hydroxy-(2S)-hexanoate 
• 123975-61-1 t-butyl 2-benzyloxycarbonylamino-3-carboxy-4-hydroxy-(2S)-hexanoate 
• 60079-12-1 β-Methyl α-tert-butyl (2S)-N-(benzyloxycarbonyl)aspartate 
• 47307-26-6 (S)-2-benzyloxycarbonylamino-succinic acid 1-tert-butyl ester 

Relevant academic research and scientific papers

ARGINASE INHIBITORS AND METHODS OF USE THEREOF

Disclosed are compounds of formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, and methods of treating cancer or a respiratory inflammatory disease using the same: (I) wherein R11 is selec

A versatile and selective chemo-enzymatic synthesis of β-protected aspartic and γ-protected glutamic acid derivatives

Two versatile, high yielding, and efficient chemo-enzymatic methods for the synthesis of β-protected Asp and γ-protected Glu derivatives using Alcalase are described. The first method is based on the α-selective enzymatic hydrolysis of symmetrical aspartyl and glutamyl diesters. The second method involving mixed diesters comprises a three-step protocol using (i) α-selective enzymatic methyl-esterification, (ii) chemical β-esterification, and finally (iii) α-selective enzymatic methyl ester hydrolysis. The yields of the purified β- and γ-esters range from 77% to 91%.

NEW ENZYMATIC APPROACH TO THE SYNTHESIS OF CONVENIENT ASPARATIC ACID INTERMEDIATES IN PEPTIDE CHEMISTRY. SYNTHESIS OF N-BENZYLOXYCARBONYL-L-ASPARATIC ACID β-ALLYL ESTER.

Asparatic acid side chain protection by allyl ester functions has been facilitated by the direct synthesis of Z-Asp(OAll)-OH which can be performed by selective hydrolysis of Z-Asp(OAll)-OAll by means of papain catalysis.Both an optimization study and a batch synthesis are reported.Other synthesis routes are discussed.

Non-Proteinogenic Amino Acid Synthesis: Synthesis of β,γ-Unsaturated α-Amino Acids from Aspartic Acid

A general, stereospecific, synthesis of β,γ-unsaturated α-amino acids using the β-anion derived from aspartic acid is described.Keywords: aspartic acid; unsaturated acids

Asymmetric Amino Acid Synthesis: Preparation of the β Anion derived from Aspartic Acid

(S)-1-t-Butyl 4-methyl N-benzyloxycarbonylaspartate (5a), and (S)-1-t-butyl 4-allyl N-benzyloxycarbonylaspartate (5b) have been synthesized from (S)-aspartic acid (2), and can be readily alkylated and hydroxyalkylated at the β-carbon for asymmetric amino acid synthesis.