99793-84-7Relevant academic research and scientific papers
Synthesis of [18F]PS13 and evaluation as a PET radioligand for cyclooxygenase-1 in monkey
Taddei, Carlotta,Morse, Cheryl L.,Kim, Min-Jeong,Liow, Jeih-San,Santamaria, Jose Montero,Zhang, Andrea,Manly, Lester S.,Zanotti-Fregonara, Paolo,Gladding, Robert L.,Zoghbi, Sami S.,Innis, Robert B.,Pike, Victor W.
, p. 517 - 530 (2021/02/16)
Cyclooxygenase-1 (COX-1) and its isozyme COX-2 are key enzymes in the syntheses of prostanoids. Imaging of COX-1 and COX-2 selective radioligands with positron emission tomography (PET) may clarify how these enzymes are involved in inflammatory conditions
IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS
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Page/Page column 86, (2010/02/07)
A compound of the formula (I): or salts thereof, which are useful for treatment and/or prevention of inflammatory conditions, various pains, collagen diseases, autoimmune diseases, thrombosis, cancer or neurodengenerative diseases.
Triazole derivatives
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, (2008/06/13)
A compound of the formula (I): wherein R1 is lower alkyl which is optionally substituted with halogen, cyano, N,N-di(lower)alkylcarbamoyl, phenyl optionally substituted with halogen, or heterocyclic group, cyclo(lower)alkyl, lower alkynyl, or N
