99838-62-7Relevant academic research and scientific papers
(R)-2,3-cyclohexylideneglyceraldehyde, a chiral pool synthon for the synthesis of 2-azido-1,3-diols
Rouf, Abdul,Aga, Mushtaq A.,Kumar, Brijesh,Taneja, Subhash C.
, p. 823 - 833 (2015/06/25)
A new approach was proposed for the synthesis of 2-azido-1,3-diols from easily available and inexpensive chiral pool synthon (R)-2,3-O-cyclohexylidene-D-glyceraldehyde, through Mitsunobu azidation of 1,2-diols. Both C(2) and C(1) azides in variable ratios
An expedient total synthesis of optically active piperidine and indolizidine alkaloids (-)-β-conhydrine and (-)-lentiginosine
Kamal, Ahmed,Vangala, Saidi Reddy
experimental part, p. 1341 - 1347 (2011/04/12)
Attempts directed toward the stereocontroled total synthesis of piperidine and indolizidine alkaloids resulted in the synthesis of (-)-β-conhydrine 1 and (-)-lentiginosine 3. The synthesis of 1 and 3 were developed from protected d-mannitol as the chiral
A novel stereoselective synthesis of (-)-β-conhydrine from (R)-2,3-O-cyclohexylidine glyceraldehyde
Venkataiah, Mallam,Fadnavis, Nitin W.
experimental part, p. 6950 - 6952 (2009/12/09)
A novel stereoselective synthesis of (-)-β-conhydrine is achieved. Stereoselective Grignard reaction of (R)-2,3-O-cyclohexylidine glyceraldehyde with ethyl magnesium bromide, chelation controlled stereoselective Grignard reaction of allyl imine derivative
Enantio- and Diastereocontrolled Synthesis of Chiral 1,2-Diol Derivatives from (R)-2,3-Di-O-isopropylideneglyceraldehyde: endo- and exo-Brevicomin
Mulzer, Johann,Angermann, Alfred,Muench, Winfried
, p. 825 - 838 (2007/10/02)
All four possible stereoisomers of the insect pheromone brevicomin have been prepared from (R)-2,3-di-O-isopropylideneglyceraldehyde (1) on stereocontrolled routes with ee more than 98-99percent.
