99838-63-8

Upstream product

• 99884-73-8 (2R)-3-benzyloxy-1-tosyloxy-2-pentanol 
• 99884-73-8 (2R,3S)-3-benzyloxy-1-tosyloxy-2-pentanol 
• 99838-62-7 (2R,3S)-3-(benzyloxy)pentane-1,2-diol 
• 115586-67-9 (2R,3S)-3-O-benzyl-4-pentene-1,2,3-triol 
• 100017-22-9 (S)-1-[(R)-oxiran-2-yl]prop-2-enol 
• 922-65-6 divinylcarbinol 
• 333788-77-5 (2R,3R)-2-Benzyloxy-3-(1-methoxy-1-methyl-ethoxy)-succinic acid diethyl ester 
• 333788-79-7 (2S,3S)-3-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-pentan-2-ol 
• 333788-78-6 (2S,3S)-2-Benzyloxy-3-(1-methoxy-1-methyl-ethoxy)-butane-1,4-diol 
• 108740-35-8 (2S,3S)-3-Benzyloxy-pentane-1,2-diol 
• 131446-96-3 (S)-2-(benzyloxy)-2-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethyl 4-methylbenzenesulfonate 
• 84379-53-3 2-O-benzyl-3,4-O-isopropylidene-L-threitol 
• 333788-80-0 Methanesulfonic acid (1S,2S)-2-benzyloxy-1-(tert-butyl-dimethyl-silanyloxymethyl)-butyl ester 
• 110009-21-7 (2R,3S)-1,2-epoxy-3-benzyloxy-4-pentene 

Downstream Products

• 102357-83-5 (4R,5S)-5-Benzyloxy-1-(2-methyl-[1,3]dioxolan-2-yl)-heptan-4-ol 
• 104487-72-1 (2R,3S)-3-O-benzyl-1-methoxymethyl-2,3-pentanediol 
• 333788-81-1 (4R,5S)-5-Benzyloxy-hept-1-yn-4-ol 
• 1268624-30-1 (3S,4R)-3-(benzyloxy)-8-(tetrahydro-2H-pyran-2-yloxy)octan-4-ol 
• 1268624-31-2 2-((5S,6S)-5-azido-6-(benzyloxy)octyloxy)-tetrahydro-2H-pyran 
• 1268624-32-3 (5S,6S)-5-azido-6-(benzyloxy)octan-1-ol 
• 1268624-33-4 (5S,6S)-5-azido-6-(benzyloxy)octyl 4-methylbenzenesulfonate 
• 1268624-29-8 (3S,4R)-3-(benzyloxy)-8-(tetrahydro-2H-pyran-2-yloxy)oct-6-yn-4-ol 
• 104487-71-0 (2R,3R)-1,2-epoxy-3-O-(p-nitrobenzoyl)-3-pentanol 
• 102357-85-7 Methanesulfonic acid (1R,2S)-2-benzyloxy-1-[3-(2-methyl-[1,3]dioxolan-2-yl)-propyl]-butyl ester 
• 80928-07-0 (4S,5S)-5-Benzyloxy-1-(2-methyl-[1,3]dioxolan-2-yl)-heptan-4-ol 
• 333788-83-3 Methanesulfonic acid (Z)-(1R,6R,7S)-7-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-1-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-(4-methoxy-benzyloxy)-ethyl]-non-3-enyl ester 
• 333788-71-9 (2R,3R,8R,9S)-9-Benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-1-(4-methoxy-benzyloxy)-undec-5-yn-3-ol 
• 333788-82-2 (Z)-(2R,3R,8R,9S)-9-Benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-1-(4-methoxy-benzyloxy)-undec-5-en-3-ol 

Relevant academic research and scientific papers

An expedient total synthesis of optically active piperidine and indolizidine alkaloids (-)-β-conhydrine and (-)-lentiginosine

Attempts directed toward the stereocontroled total synthesis of piperidine and indolizidine alkaloids resulted in the synthesis of (-)-β-conhydrine 1 and (-)-lentiginosine 3. The synthesis of 1 and 3 were developed from protected d-mannitol as the chiral

The first total synthesis of (+)-rogioloxepane A

The first total synthesis of (+)-rogioloxepane A is described. The α,ω-trans-disubstituted oxepene skeleton was stereoselectively constructed via cyclization of the hydroxy epoxide promoted by the (Bu3Sn)2O/Zn(OTf)2 system. The proposed configurations of 6R and 13R were confirmed through this synthetic study.

Enantio- and Diastereocontrolled Synthesis of Chiral 1,2-Diol Derivatives from (R)-2,3-Di-O-isopropylideneglyceraldehyde: endo- and exo-Brevicomin

All four possible stereoisomers of the insect pheromone brevicomin have been prepared from (R)-2,3-di-O-isopropylideneglyceraldehyde (1) on stereocontrolled routes with ee more than 98-99percent.

Preparation of (2R,3S)-1,2-Epoxypent-4-en-3-ol, a New Chiral Building Block for the Synthesis of (+)-endo- and (-)-exo-Brevicomin

Asymmetric epoxidation of the divinylcarbinol (7) using L-(+)-diethyl tartrate gave (2r,3S)-1,2-epoxypent-4-en-3-ol (8), which was utilized as a chiral building block in the synthesis of (+)-endo- and (-)-exo-brevicomin.