99838-63-8Relevant academic research and scientific papers
An expedient total synthesis of optically active piperidine and indolizidine alkaloids (-)-β-conhydrine and (-)-lentiginosine
Kamal, Ahmed,Vangala, Saidi Reddy
experimental part, p. 1341 - 1347 (2011/04/12)
Attempts directed toward the stereocontroled total synthesis of piperidine and indolizidine alkaloids resulted in the synthesis of (-)-β-conhydrine 1 and (-)-lentiginosine 3. The synthesis of 1 and 3 were developed from protected d-mannitol as the chiral
The first total synthesis of (+)-rogioloxepane A
Matsumura, Ryuji,Suzuki, Toshio,Hagiwara, Hisahiro,Hoshi, Takashi,Ando, Masayoshi
, p. 1543 - 1546 (2007/10/03)
The first total synthesis of (+)-rogioloxepane A is described. The α,ω-trans-disubstituted oxepene skeleton was stereoselectively constructed via cyclization of the hydroxy epoxide promoted by the (Bu3Sn)2O/Zn(OTf)2 system. The proposed configurations of 6R and 13R were confirmed through this synthetic study.
Enantio- and Diastereocontrolled Synthesis of Chiral 1,2-Diol Derivatives from (R)-2,3-Di-O-isopropylideneglyceraldehyde: endo- and exo-Brevicomin
Mulzer, Johann,Angermann, Alfred,Muench, Winfried
, p. 825 - 838 (2007/10/02)
All four possible stereoisomers of the insect pheromone brevicomin have been prepared from (R)-2,3-di-O-isopropylideneglyceraldehyde (1) on stereocontrolled routes with ee more than 98-99percent.
Preparation of (2R,3S)-1,2-Epoxypent-4-en-3-ol, a New Chiral Building Block for the Synthesis of (+)-endo- and (-)-exo-Brevicomin
Hatakeyama, Susumi,Sakurai, Kuniya,Takano, Seiichi
, p. 1759 - 1761 (2007/10/02)
Asymmetric epoxidation of the divinylcarbinol (7) using L-(+)-diethyl tartrate gave (2r,3S)-1,2-epoxypent-4-en-3-ol (8), which was utilized as a chiral building block in the synthesis of (+)-endo- and (-)-exo-brevicomin.
