99841-23-3Relevant academic research and scientific papers
Conversion of N-benzyloxycarbonylamino- and N-Tosylamino-benzyl phenylsulfones by green Strecker reactions to α-aminobenzyl nitriles using potassium hexacyanoferrate(II)
Hu, Xiaochun,Li, Rongzhi,Li, Zheng
, p. 432 - 436 (2014/08/05)
The cyanation of aldimines, generated in situ from N- benzyloxycarbonylamino- and N-tosylamino-benzyl phenylsulfones, to the corresponding N-protected a-aminobenzyl nitriles has been achieved by eco-friendly Strecker reactions using potassium hexacyanofer
Hydrocyanation of sulfonylimines using potassium hexacyanoferrate(II) as an eco-friendly cyanide source
Li, Zheng,Li, Rongzhi,Zheng, Huanhuan,Wen, Fei,Li, Hongbo,Yin, Junjun,Yang, Jingya
, p. 1739 - 1743 (2014/01/06)
An efficient and eco-friendly method for hydrocyanation of sulfonylimines via one-pot two-step procedure using potassium hexacyanoferrate(II) as a cyanide source, benzoyl chloride as a promoter, and potassium carbonate as a base is described. This protocol has the features of using nontoxic, nonvolatile and inexpensive cyanide source, high yield, and simple work-up procedure.
Synthesis of α-aminonitriles through Strecker reaction of N-tosylaldimines using molecular iodine
Das, Biswanath,Balasubramanyam, Penagaluri,Krishnaiah, Maddeboina,Veeranjaneyulu, Boyapati,Reddy, Gandolla Chinna
experimental part, p. 3467 - 3471 (2010/02/28)
The Strecker reaction of N-tosylaldimines with trimethylsilyl cyanide in the presence of catalytic amount of iodine at room, temperature produces the corresponding protected α-aminonitriles in high yields.
Benzotriazole-assisted synthesis of N-(α-cyanoalkyl)sulfonamides
Katritzky, Alan R.,Oniciu, Daniela C.,Ghiviriga, Ion
, p. 907 - 922 (2007/10/03)
N-(α-benzotriazol-1-ylalkyl)sulfonamides, readily available from benzotriazole, an aldehyde and a sulfonamide, are converted into the corresponding N-(α-cyanoalkyl)sulfonamides in good yields by treatment with potassium cyanide.
