163926-77-0

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-propylidene-
• CAS NO: 163926-77-0
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.285
• Mol File: 163926-77-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-propylidene-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-propylidene-(163926-77-0)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-propylidene-(163926-77-0)

Safety Data

• Hazardous Substances Data: 163926-77-0(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 123-38-6 propionaldehyde 
• 4104-47-6 N-sulfinyl-p-toluenesulfonamide 
• 163926-85-0 N-[2-Ethyl-1λ⁴-naphtho[1,8-de][1,3]dithiin-(1E)-ylidene]-4-methyl-benzenesulfonamide 

Downstream Products

• 99841-23-3 N-(α-cyanopropyl)-p-toluenesulfonamide 
• 1323722-93-5 (R)-N-(1-(m-tolyl)propyl)-4-methylbenzenesulfonamide 
• 1323722-87-7 (R)-N-(1-(4-(trifluoromethyl)phenyl)propyl)-4-methylbenzenesulfonamide 
• 93241-22-6 4-methyl-N-[(1R)-1-phenylpropyl]benzene-1-sulfonamide 
• 1133-12-6 N-propyl-toluene-4-sulfonamide 

Relevant articles and documents

A new method for preparation of 3,6-dihydro-2H-1,3-oxazines and explorations of their use in stereoselective synthesis of 1,3-amino alcohol derivatives

Condensation of β-hydroxy aldehydes with N-sulfonyl aldimines produces 3,6-dihydro-2H-1,3-oxazines in moderate to excellent yields. The process is stereoselective, with the C-2 and C-6 substituents having a trans relationship in these heterocycles. Some transformations of these oxazines as potential acyclic 1,3-amino alcohol synthons are described.

Dual gold catalysis: A novel synthesis of bicyclic and tricyclic pyrroles from n -propargyl ynamides

Various N-propargyl ynamides were converted to bicylic and tricyclic pyrroles by the use of a cationic dual-activation gold catalyst. This reaction starts with the nucleophilic addition of a gold acetylide onto an ynamide triple bond at the ?2-position of the nitrogen atom. Thus, gold vinylidene is formed, and then a second cyclization takes place. The formation of the gold vinylidene is indicated by the evidence that not only aryl ynamides but also alkyl ynamides undergo C-H activation in these reactions.

Highly enantioselective arylation of N -tosylalkylaldimines catalyzed by rhodium-diene complexes

A highly enantioselective rhodium-catalyzed arylation of aliphatic N-tosylaldimines has been developed. The combination of chiral bicyclo[3.3.0]octadiene ligands, an active rhodium hydroxide complex, and neutral reaction conditions is the key to achieving high yield and enantioselectivity. The application of this method is demonstrated by the enantioselective synthesis of chiral 2-aryl pyrrolidines and piperidines in a one-pot procedure. Furthermore, excellent results are also obtained for the imine substrates with the more readily cleavable N-nosyl protecting group.