99844-15-2Relevant academic research and scientific papers
Three substituted 4-pyrazolylbenzoates: Hydrogen-bonded supramolecular structures in one, two and three dimensions
Portilla, Jaime,Mata, Ernesto G.,Nogueras, Manuel,Cobo, Justo,Low, John N.,Glidewell, Christopher
, p. o21-o25 (2007)
The molecules of ethyl 4-(5-amino-3-methyl-1H-pyrazol-1-yl)benzoate, C 13H15N3O2, are linked by two independent N - H...-O hydrogen bonds into a chain of edge-fused and alternating R42(8) a
One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions
Marinozzi, Maura,Marcelli, Gloria,Carotti, Andrea,Natalini, Benedetto
, p. 7019 - 7023 (2014/02/14)
An efficient synthetic approach to synthesize N-aryl-5-aminopyrazoles from anilines via a one-pot, telescoped reaction performed in entirely aqueous conditions has been developed. This protocol provides a rapid, convenient method to prepare N-aryl-5-aminopyrazoles, useful building blocks for the synthesis of several bicyclic nitrogen heterocycles, by avoiding the isolation of the toxic intermediate arylhydrazines and the use of a metallic reductant. The Royal Society of Chemistry 2014.
