99858-14-7

Basic information

• Product Name: butan-2-yl[(2,4-dichlorophenyl)methyl]amine
• Synonyms: butan-2-yl[(2,4-dichlorophenyl)methyl]amine
• CAS NO: 99858-14-7
• Molecular Formula: C₁₁H₁₅Cl₂N
• Molecular Weight: 232.1495
• Mol File: 99858-14-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 287.8±25.0 °C(Predicted)
• Appearance: /
• Density: 1.133±0.06 g/cm3(Predicted)
• PKA: 8.65±0.19(Predicted)
• CAS DataBase Reference: butan-2-yl[(2,4-dichlorophenyl)methyl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: butan-2-yl[(2,4-dichlorophenyl)methyl]amine(99858-14-7)
• EPA Substance Registry System: butan-2-yl[(2,4-dichlorophenyl)methyl]amine(99858-14-7)

Safety Data

• Hazardous Substances Data: 99858-14-7(Hazardous Substances Data)

Usage

Uses

(Butan-2-yl)[(2,4-dichlorophenyl)methyl]amine is a useful reagent in the preparation of secondary amines via selective alkylation of primary amines with alkyl bromides.

Upstream product

• 78-76-2 s-butyl bromide 
• 95-00-1 2,4-dichloro-benzenemethanamine 

Relevant articles and documents

Selective N-alkylation of primary amines with R-NH2·HBr and alkyl bromides using a competitive deprotonation/protonation strategy

Monoalkylation of primary amines using amine hydrobromides and alkyl bromides has been carried out. Under controlled reaction conditions the reactant primary amine was selectively deprotonated and made available for reaction, while the newly generated secondary amine remained protonated, and did not participate in alkylation further. Reaction was carried out under mild reaction conditions and was applicable to a wide range of primary amines and alkyl bromides.