99862-34-7Relevant articles and documents
Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry
Corbett, David F.,Heightman, Tom D.,Moss, Stephen F.,Bromidge, Steven M.,Coggon, Sara A.,Longley, Mark J.,Roa, Ana Maria,Williams, Jennifer A.,Thomas, David R.
, p. 4014 - 4018 (2005)
High-throughput screening of an array of biphenylmethylamines synthesised by high-throughput solid-phase chemistry resulted in the identification of compounds with high-affinity for the 5-ht5A receptor. The structure-activity relationship within this series and further array synthesis led to the identification of the biphenylmethylamine derivative 11, a potent and selective 5-ht5A receptor antagonist.
