99872-44-3Relevant academic research and scientific papers
Copper-Catalyzed Tandem O-Vinylation of Arylhydroxylamines/[3,3]-Rearrangement/Cyclization: Synthesis of Highly Substituted Indoles and Benzoindoles
Yuan, Hairui,Guo, Lirong,Liu, Fengting,Miao, Zechen,Feng, Lei,Gao, Hongyin
, p. 3906 - 3912 (2019/04/25)
Herein, we developed a copper-catalyzed O-vinylation of arylhydroxylamine using vinyliodonium salts as vinylation reagents to generate a transient O-vinyl-N-arylhydroxylamine that rapidly undergoes a [3,3]-sigmatropic rearrangement and subsequent cyclizat
HFIP-promoted Bischler indole synthesis under microwave irradiation
Yao, Guangkai,Zhang, Zhi-Xiang,Zhang, Cheng-Bei,Xu, Han-Hong,Tang, Ri-Yuan
, (2019/01/03)
1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP) was found to be effective for the Bischler indole synthesis under microwave irradiation in the absence of a metal catalyst. Under the catalysis of HFIP, a wide range of α-amino arylacetones were successfully transf
Ruthenium-Catalyzed Cycloisomerization of 2-Alkynylanilides: Synthesis of 3-Substituted Indoles by 1,2-Carbon Migration
Watanabe, Takuma,Mutoh, Yuichiro,Saito, Shinichi
supporting information, p. 7749 - 7752 (2017/06/21)
We developed ruthenium-catalyzed cycloisomerization of alkynylanilides that gave 3-substituted indoles in high yields. The reaction proceeded via the disubstituted vinylidene ruthenium complex that was formed by the 1,2-carbon migration.
Aerobic palladium(II)-catalyzed dehydrogenation of cyclohexene-1-carbonyl indole amides: An indole-directed aromatization
Kandukuri, Sandeep R.,Oestreich, Martin
, p. 8750 - 8755 (2012/11/07)
A palladium(II)-catalyzed oxidative dehydrogenation of cyclohexene-1- carbonyl indole amides yielding the corresponding benzoylindoles is reported. The new aromatization is also applied to functionalized indoles such as tryptamine and tryptophan. The tethered indole is likely acting as a directing group for allylic C-H bond activation, and there is evidence for a mechanism proceeding through 1,3-diene formation followed by aromatization.
Process for producing indoline compounds and intermediates for the production of the same
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, (2008/06/13)
This invention concerns a method for the production of a 3-arylindoline compound represented by the general formula STR1
