99893-05-7

Basic information

• Product Name: 1-methyl-piperidin-4-one-phenylhydrazone
• CAS NO: 99893-05-7
• Molecular Weight: 203.287
• Mol File: 99893-05-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-piperidin-4-one-phenylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-piperidin-4-one-phenylhydrazone(99893-05-7)
• EPA Substance Registry System: 1-methyl-piperidin-4-one-phenylhydrazone(99893-05-7)

Safety Data

• Hazardous Substances Data: 99893-05-7(Hazardous Substances Data)

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 59-88-1 phenylhydrazine hydrochloride 
• 100-63-0 phenylhydrazine 

Downstream Products

• 1314139-45-1 C₂₀H₂₇N₃O₂ 
• 101589-72-4 N-(1-methyl-[4]piperidyl)-N'-phenyl-hydrazine 
• 5094-12-2 2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 

Relevant articles and documents

1,3-dipolar cycloaddition of hydrazones with α-oxo-ketenes: A three-component stereoselective entry to pyrazolidinones and an original class of spirooxindoles

Stereodefined monocyclic, spirobicyclic, and bis-spirotricyclic pyrazolidin-3-ones can be prepared efficiently by a three-component reaction involving a 1,3-dipolar cycloaddition of azomethine imines obtained from hydrazones with α-oxo-ketene dipolarophiles generated in situ. The reaction allows the creation of four covalent bonds and two contiguous chiral quaternary centers with excellent diastereoselectivity in a single catalyst/additive-free, highly atom-economical transformation. From a fundamental point of view, the reaction introduces α-oxo-ketenes as effective dipolarophiles in 1,3-dipolar cycloadditions.