999-61-1

Basic information

• Product Name: 2-HYDROXYPROPYL ACRYLATE
• Synonyms: 2-Hydroxypropyl acry;2HPA;Kayarad HPA;Light Ester HOP-A;2-HYDROXYPROPYL ACRYLATE;PROPYLENE GLYCOL MONOACRYLATE;1,2-propanediol,1-acrylate;1,2-propanediol1-acrylate
• CAS NO: 999-61-1
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.14
• EINECS: 213-663-8
• Product Categories: Industrial/Fine Chemicals;monomer
• Mol File: 999-61-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 77°C 5mm
• Flash Point: 79.9 °C
• Appearance: /
• Density: 1.06 g/cm3
• Vapor Pressure: 0.115mmHg at 25°C
• Refractive Index: 1.4315 (estimate)
• PKA: 13.92±0.20(Predicted)
• Water Solubility: 150,000 mg l-1 (e)
• CAS DataBase Reference: 2-HYDROXYPROPYL ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXYPROPYL ACRYLATE(999-61-1)
• EPA Substance Registry System: 2-HYDROXYPROPYL ACRYLATE(999-61-1)

Safety Data

• Statements: 23/24/25-34-43
• Safety Statements: 26-36/37/39-45
• RIDADR: 2927
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 999-61-1(Hazardous Substances Data)

Usage

Description

A case of occupational contact dermatitis caused by exposure to 2-hydroxypropyl acrylate was reported in industry.

Chemical Properties

A liquid.

Uses

Different sources of media describe the Uses of 999-61-1 differently. You can refer to the following data:
1. In manufacture of thermosetting resins for surface coatings.
2. Monomer used in manufacture of thermosetting resins for surface coatings.

Definition

A functional monomer used in manufacture of thermosetting acrylic resins for surface coatings.

Hazard

TLV: 0.5 ppm. Corrosive to skin and eyes. Toxic by skin absorption.

Health Hazard

2-Hydroxypropyl acrylate is an irritant of the eyes, nose, respiratory tract, and skin.

InChI:InChI=1/C6H10O3/c1-3-6(8)9-4-5(2)7/h3,5,7H,1,4H2,2H3/t5-/m0/s1

Upstream product

• 2421-07-0 2-ethenyl-4-methyl-1,3-dioxolane 
• 57-55-6 propylene glycol 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 52723-96-3 (4-methyl-1,3-phenylene)bis[iminocarbonyloxy(2-methyl-2,1-ethanediyl)] diacrylate 
• 51727-50-5 acrylic acid 2-phenylcarbamoyloxy-propyl ester 

Relevant articles and documents

Hydroxy functional acrylate and methacrylate monomers prepared via lipase-catalyzed transacylation reactions

Candida antarctica lipase B (CAL-B, Novozyme 435) catalyzes the transacylation of methyl acrylate and methyl methacrylate with diols and triols in 2-methyl-2-butanol at 50 °C. Under the experimental conditions, up to 70 mol% of the acyl donor methyl acrylate was converted. Methyl methacrylate is the less efficient acyl donor (up to 60 mol%) due to the higher sterical hindrance in the enzymatic transacylation. Under the reaction conditions high yields of the mono-acylated products are obtained, which contain minor amounts of bis(meth)acrylates. In addition it was observed that Novozyme 435 catalyzes regioselectively the acylation of the primary hydroxyl groups. In comparison with the chemical catalyzed route no selectivity was observed for unsubstituted diols. For substituted diols more mono-acylated product was formed in the lipase-catalyzed reaction than in the chemical catalyzed reaction.

Wet adhesion promoter

Compositions containing urea functional compounds are disclosed which are particularly suitable for use as post-added wet adhesion promoters in coatings, especially in aqueous emulsion systems used to make latex paints. A process of preparing the same is also disclosed, as well as a novel class of compounds.