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Usage

Uses

Used in Textile Industry:
2-Bromoethylphosphonic acid is used as a flame retardant to enhance the fire resistance of textiles, providing safety and durability to fabrics used in various applications, including clothing, upholstery, and industrial materials.
Used in Plastics Industry:
In the plastics industry, 2-Bromoethylphosphonic acid serves as a flame retardant, improving the safety characteristics of plastic products by reducing their flammability and potential fire hazards.
Used in Pharmaceutical Synthesis:
2-Bromoethylphosphonic acid is utilized as a key intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Synthesis:
2-BROMOETHYLPHOSPHONIC ACID is also employed in the production of agrochemicals, playing a role in the synthesis of pesticides and other agricultural chemicals that help protect crops and enhance agricultural productivity.

Upstream product

• 69310-54-9 bis(trimethylsilyl) (2-bromoethyl)phosphonate 
• 19247-79-1 β-Brom-ethyl-phosphor-dibromid 
• 5324-30-1 diethyl 2-bromoethylphosphonate 
• 28482-01-1 (2-bromoethyl)phosphonic dichloride 

Relevant academic research and scientific papers

Comments on a New Simple Route to N-Substituted 2-Aminoethylphosphonic Acids. A Reinvestigation

A recent article[11] reported a new route to 2-aminoethylphosphonic acid and its N-alkyl derivatives by ammonolysis and aminolysis of 2-chloroethylphosphonic acid. Attempts to reproduce these reactions failed to give aminophosphonic acids and led only to unreacted amine and phosphates with evolution of ethylene.

Dealkylation of dialkyl phosphonates with boron tribromide

Boron tribromide cleanly and quantitatively converts dimethyl-, diethyl-, diisopropyl-, and ditertiobutyl phosphonates RP(O)(OR')2 into the corresponding phosphonic acids RP(O)(OH)2 via methanolysis. The use of boron tribromide is compatible with a variety of functionalities in the R group.

AN APPROACH TOWARDS THE FORMATION OF AN ESTER BOND BETWEEN THE PRIMARY HIDROXYL OF A β-D-GALACTOPYRANOSIDE AND 2-AMINOETHYLPHOSPHONIC ACID AND ITS N-METHYL SUBSTITUTED DERIVATIVES

An expeditious method for the preparation of the phosphonylating reagent 2-bromo-ethylphosphonic acid is presented.The latter compound as well as salicylchlorophosphite proved to be suitable for the synthesis of methyl O-6-(2'-aminoethyl-phosphonyl)-β-D-g

Phosphocholine derivatives having antihypertensive action

Phosphocholine derivatives and compositions are described which are useful as hypotensive agents and in the treatment of hypertension in warm-blooded animals.

Synergistic herbicidal compositions

Synergistic herbicidal activity is displayed by compositions comprising the following two components: (a) a pyrrolidone of the formula STR1 in which X is selected from the group consisting of hydrogen, chlorine and methyl; Y is selected from the group consisting of hydrogen, chlorine and bromine; Z is selected from the group consisting of chlorine and bromine; R1 is selected from the group consisting of hydrogen and C1 -C4 alkyl; R2 is selected from the group consisting of hydrogen, halogen, C1 -C4 alkyl, acetyl, trifluoromethyl, nitro, cyano, C1 -C4 alkoxy, C1 -C4 alkylthio, C1 -C4 alkylsulfinyl, C1 -C4 alkylsulfonyl, trifluoromethylsulfinyl, trifluoromethylsulfonyl, pentafluoropropionamido, and 3-methylureido; and R3 is selected from the group consisting of hydrogen, C1 -C4 alkyl, chlorine and trifluoromethyl; and (b) a phosphonic acid of the formula STR2 in which R4 is selected from the group consisting of C1 -C4 alkyl, C1 -C4 haloalkyl, and --CH2 NHCH2 COOH, at a weight ratio of (a) to (b) of from about 0.1:1 to about 20:1.

The Dealkylation of Phosphate and Phosphonate Esters by Iodotrimethylsilane: A Mild and Selective Procedure

Iodotrimethylsilane transforms alkyl esters of phosphorus oxyacids into their corresponding trimethylsilyl esters and alkyl iodide.The reaction is rapid and quantitative at room temperature.The reagent has no effect on aryl phosphate ester functions or upon alkyl carboxylate, ether, bromoalkane, vinyl, and ethynyl functions under the conditions employed for transesterification.The trimethylsilyl esters can be isolated by distillation or solvolysed without purification using methanol or water to afford dealkylated phosphate and phosphonate species.Selective monodealkylation of dialkyl phosphonates cannot be achieved using only one equivalent of the reagent, wich leads to the formation of mixed products.