28482-01-1

Usage

Uses

Used in Flame Retardant Production:
(2-bromoethyl)phosphonic dichloride is used as an intermediate in the production of flame retardants, which are essential for enhancing the fire resistance of various materials.
Used in Water Treatment Chemicals:
In the water treatment industry, (2-bromoethyl)phosphonic dichloride serves as a precursor for developing chemicals that help in purifying water and maintaining water quality.
Used in Agrochemicals:
(2-bromoethyl)phosphonic dichloride is utilized as a component in the synthesis of agrochemicals, contributing to the development of products that protect crops and enhance agricultural productivity.
Used in Pharmaceutical Industry:
(2-bromoethyl)phosphonic dichloride is employed as a building block in the pharmaceutical sector for the development of potential drug candidates, highlighting its importance in creating new medicines.

Upstream product

• 78-45-5 (2-bromo-ethyl)-phosphonic acid bis-(2-bromo-ethyl ester) 
• 106-93-4 ethylene dibromide 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 10026-13-8 phosphorus pentachloride 
• 69310-54-9 bis(trimethylsilyl) (2-bromoethyl)phosphonate 

Downstream Products

• 999-82-6 (2-bromoethyl)phosphonic acid 
• 18498-26-5 1-O-hexadecanoyl-3-O-<<2-(trimethylamino)ethyl>phosphoryl>propanediol 
• 98899-65-1 2-O-Benzyl-1-O-hexadecylglyceryl-3-(2-bromethyl-phosphonat) 

Relevant academic research and scientific papers

The synthesis of methylated, phosphorylated, and phosphonated 3′-aminoacyl-tRNASec mimics

The twenty first amino acid, selenocysteine (Sec), is the only amino acid that is synthesized on its cognate transfer RNA (tRNASec) in all domains of life. The multistep pathway involves O-phosphoseryl-tRNA: selenocysteinyl-tRNA synthase (SepSe

Experimental and theoretical investigation of intramolecular transformations of silicon-containing (haloalkyl)phosphorylated ureas and acylamides

Silicon-containing chloromethylphosphorylated ureas undergo transformation involving evolution of chlorotrimethylsilane and formation of 1,3,4-oxazaphospholes. Their analogs, silicon-containing phosphorylated acylamides, transform in another way, viz. by

Reaction of dibromoalkanes with silyl phosphites. Synthesis and properties of mono-and diphosphonoalkanes

Reactions of dibromoethane and dibromopropane with silyl phosphites are studied. Mono-and diphosphonoalkanes of various structures were prepared, and their chemical properties were studied. Pleiades Publishing, Inc., 2006.

Cationic phosphonolipids containing quaternary phosphonium and arsonium groups for DNA transfection with good efficiency and low cellular toxicity

Replacing the ammonium polar head in cationic lipids 1 (A = N) by a phosphonium or an arsonium group (A=P, As) improves their properties as synthetic vectors for DNA transfection. The increased volume of the cationic head is supposed to modify the interactions of the vector with the solvent and DNA.

A NEW AND VERSATILE PHOSPHONYLATION APPROACH

The bifunctional reagent bis(benzotriazolyl)-2-bromoethylphosphonate has been used successfully for the preparation of 2-amino-, 2-N-methylamino- and 2-N-dimethylaminoethylphosphonates of methyl 2,3,4-tri-O-benzoyl-β-D-galactopyranoside.