28482-01-1Relevant academic research and scientific papers
The synthesis of methylated, phosphorylated, and phosphonated 3′-aminoacyl-tRNASec mimics
Rigger, Lukas,Schmidt, Rachel L.,Holman, Kaitlyn M.,Simonovic, Miljan,Micura, Ronald
supporting information, p. 15872 - 15878 (2014/04/03)
The twenty first amino acid, selenocysteine (Sec), is the only amino acid that is synthesized on its cognate transfer RNA (tRNASec) in all domains of life. The multistep pathway involves O-phosphoseryl-tRNA: selenocysteinyl-tRNA synthase (SepSe
Reaction of dibromoalkanes with silyl phosphites. Synthesis and properties of mono-and diphosphonoalkanes
Pudovik,Terent'eva,Kibardina,Pudovik
, p. 714 - 719 (2008/02/02)
Reactions of dibromoethane and dibromopropane with silyl phosphites are studied. Mono-and diphosphonoalkanes of various structures were prepared, and their chemical properties were studied. Pleiades Publishing, Inc., 2006.
Experimental and theoretical investigation of intramolecular transformations of silicon-containing (haloalkyl)phosphorylated ureas and acylamides
Pudovik,Chmutova,Kibardina,Terent'eva,Bagautdinova,Khailova,Kamalov,Pudovik
, p. 376 - 380 (2008/02/05)
Silicon-containing chloromethylphosphorylated ureas undergo transformation involving evolution of chlorotrimethylsilane and formation of 1,3,4-oxazaphospholes. Their analogs, silicon-containing phosphorylated acylamides, transform in another way, viz. by
Cationic phosphonolipids containing quaternary phosphonium and arsonium groups for DNA transfection with good efficiency and low cellular toxicity
Guenin, Erwann,Herve, Anne-Cecile,Floch, Virginie,Loisel, Severine,Yaouanc, Jean-Jacques,Clement, Jean-Claude,Ferec, Claude,Des Abbayes, Herve
, p. 629 - 631 (2007/10/03)
Replacing the ammonium polar head in cationic lipids 1 (A = N) by a phosphonium or an arsonium group (A=P, As) improves their properties as synthetic vectors for DNA transfection. The increased volume of the cationic head is supposed to modify the interactions of the vector with the solvent and DNA.
A NEW AND VERSATILE PHOSPHONYLATION APPROACH
Klein, P.A.M. van der,Dreef, C.E.,Marel, G.A. van der,Boom, J.H. van
, p. 5473 - 5476 (2007/10/02)
The bifunctional reagent bis(benzotriazolyl)-2-bromoethylphosphonate has been used successfully for the preparation of 2-amino-, 2-N-methylamino- and 2-N-dimethylaminoethylphosphonates of methyl 2,3,4-tri-O-benzoyl-β-D-galactopyranoside.
