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5-Phenyl-1,3-oxazole-4-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 99924-18-2 Structure
  • Basic information

    1. Product Name: 5-Phenyl-1,3-oxazole-4-carboxylic acid
    2. Synonyms: BUTTPARK 153\57-35;5-PHENYL-OXAZOLE-4-CARBOXYLIC ACID;5-PHENYL-1,3-OXAZOLE-4-CARBOXYLIC ACID;5-Phenyl-1,3-oxazole-4-carboxylic acid ,97%;5-phenyl-1,3-oxazole-4-carboxylic acid(SALTDATA: FREE);4-Carboxy-5-phenyl-1,3-oxazole
    3. CAS NO:99924-18-2
    4. Molecular Formula: C10H7NO3
    5. Molecular Weight: 189.17
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 99924-18-2.mol
  • Chemical Properties

    1. Melting Point: 181 °C
    2. Boiling Point: 354.73 °C at 760 mmHg
    3. Flash Point: 168.335 °C
    4. Appearance: /
    5. Density: 1.32 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.587
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 5-Phenyl-1,3-oxazole-4-carboxylic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-Phenyl-1,3-oxazole-4-carboxylic acid(99924-18-2)
    12. EPA Substance Registry System: 5-Phenyl-1,3-oxazole-4-carboxylic acid(99924-18-2)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36/37/39-37/39
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 99924-18-2(Hazardous Substances Data)

99924-18-2 Usage

Chemical Properties

White solid

Check Digit Verification of cas no

The CAS Registry Mumber 99924-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,9,2 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 99924-18:
(7*9)+(6*9)+(5*9)+(4*2)+(3*4)+(2*1)+(1*8)=192
192 % 10 = 2
So 99924-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H7NO3/c12-10(13)8-9(14-6-11-8)7-4-2-1-3-5-7/h1-6H,(H,12,13)

99924-18-2Relevant articles and documents

Oxazole Synthesis by Sequential Asmic-Ester Condensations and Sulfanyl-Lithium Exchange-Trapping

Mueller, Louis G.,Chao, Allen,Alwedi, Embarek,Natrajan, Maanasa,Fleming, Fraser F.

, p. 1500 - 1503 (2021/03/08)

Oxazoles are rapidly assembled through a sequential deprotonation-condensation of Asmic, anisylsulfanylmethylisocyanide, with esters followed by sulfanyl-lithium exchange-trapping. Deprotonating Asmic affords a metalated isocyanide that efficiently traps esters to afford oxazoles bearing a versatile C-4 anisylsulfanyl substituent. Interchange of the anisylsulfanyl substituent is readily achieved through a first-in-class sulfur-lithium exchange-electrophilic trapping sequence whose versatility is illustrated in the three-step synthesis of the bioactive natural product streptochlorin.

Metalation of 4-oxazolinyloxazole derivatives. A convenient route to 2,4-bifunctionalized oxazoles.

Couture, Axel,Grandclaudon, Pierre,Hoarau, Christophe,Cornet, Josephine,Henichart, Jean-Pierre,Houssin, Raymond

, p. 3601 - 3606 (2007/10/03)

The synthesis of an array of 5-phenyloxazole derivatives bearing a variety of hydroxyalkyl groups at the C-2 position of the heterocyclic nucleus and possessing a formyl or a carboxyl function at C-4 is reported. These bifunctionalized compounds have been efficiently prepared by addition of carbonylated electrophiles to the 2-lithio derivative of 5-phenyloxazole preliminarily equipped with an oxazoline unit at the 4-position of the oxazole nucleus. It is demonstrated that this protocol offers a double advantage since it suppresses the troublesome electrocyclic ring-opening reaction and allows access to the target compounds by simple chemical transformation of the oxazoline ring system.

Synthesis and hypolipidemic activities of 5-thienyl-4-oxazoleacetic acid derivatives

Moriya,Takabe,Maeda,Matsumoto,Takashima,Takeyama

, p. 333 - 341 (2007/10/02)

A series of 2,5-disubstituted 4-oxazoleacetic acid derivatives was synthesized and evaluated for hypolipidemic activity. Among them, those with a thienyl group at C-5 of the oxazole ring exerted highly potent hypolipidemic effects in rats. 2-(4-Fluorophen

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