99948-46-6Relevant articles and documents
Transition-Metal-Free α-Arylation of Enolizable Aryl Ketones and Mechanistic Evidence for a Radical Process
Pichette Drapeau, Martin,Fabre, Indira,Grimaud, Laurence,Ciofini, Ilaria,Ollevier, Thierry,Taillefer, Marc
, p. 10587 - 10591 (2015)
The α-arylation of enolizable aryl ketones can be carried out with aryl halides under transition-metal-free conditions using KOtBu in DMF. The α-aryl ketones thus obtained can be used for step- and cost-economic syntheses of fused heterocycles and Tamoxifen. Mechanistic studies demonstrate the synergetic role of base and solvent for the initiation of the radical process.
Simple and efficient method for tetrahydropyranylation of alcohols and phenols by using silica supported sodium hydrogen sulphate as a catalyst
Ravi Kumar,Satyanarayana,Srinivasa Reddy
experimental part, p. 3876 - 3878 (2012/09/21)
A Simple and efficient process for tetrahydropyranylation of alcohols and phenols has been developed by reacting with dihydropyran at room temperature in presence of catalytic amount of silica supported sodium hydrogen sulphate.
Aza Hopf cyclization: synthesis and reactivity of cyclic azadieneynes
Mandal, Sayantan,Basak, Amit
scheme or table, p. 3641 - 3644 (2009/09/30)
Nine- and 10-membered azadieneynes have been synthesized for the first time via an intramolecular aza Wittig reaction. The compounds undergo Hopf cyclization under ambient conditions to the hydroxy dihydroisoquinoline derivatives.