99985-60-1

Upstream product

• 3097-74-3 methyl malonic acid methyl ester 
• 100-61-8 N-methylaniline 
• 100-42-5 styrene 
• 5445-17-0 Methyl 2-bromopropionate 

Relevant academic research and scientific papers

Synthesis of γ-Amino Esters by Copper-Catalyzed Intermolecular 1,2-Aminoalkylation of Alkenes with Amines and α-Bromoalkyl Esters

A new copper-catalyzed intermolecular 1,2-aminoalkylation of alkenes with α-bromoalkyl esters and amines for the synthesis of γ-amino esters is described. Employing the Cu(OTf) 2 and 2,2′-bipyridine catalytic system, the three-component reaction allows the formation of two new chemical bonds, including one C-C bond and one C-N bond, in a single reaction, and represents a new alkene difunctionalization using a radical strategy.

A new strategy for the construction of α-amino acid esters via decarboxylation

A new α-amino acid esters formation reaction has been developed via decarboxylation. The methodology is distinguished by its practical novelty in terms of the readily accessible starting materials, environmentally benign reaction conditions and waste streams, and wide substrate scope.