CAS : 9041-07-0
SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
1. Identification of the substance/preparation and of the company/undertaking
Trade name : Natrulon HT
Company : Lonza Ltd
Muenchensteinerstrasse 38
CH-4002 Basel, Switzerland
Telephone: +41 61 316 81 11
Emergency telephone : Lonza Ltd, CH-4002 Basel, Switzerland
Telephone: +41 61 313 94 94 (24h)
Contact person : prodinfo@lonza.com
2. Hazards identification
Classification
May cause sensitization by inhalation.
3. Composition/information on ingredients
Components / EC Label Concentration
Glycerol (CAS-No.: 56-81-5) (EEC-No.: 200-289-5) 47 - 50 % (*)
Papain (CAS-No.: 9001-73-4) (EEC-No.: 232-627-2) Xn; R36/37/38, 2 - 15 %
R42
Decaglycerol (CAS-No.: 9041-07-0) (EEC-No.: 232-921-0) 1- 3%
Water (CAS-No.: 7732-18-5) (EEC-No.: 231-791-2) 35 - 45 %
R-phrase(s) See chapter 16
(*) Components with workplace control parameters See chapter 8
4. First aid measures
Inhalation : Remove to fresh air. If breathing is irregular or stopped,
administer artificial respiration. If symptoms persist, call a
physician.
Skin contact : After contact with skin, wash immediately with plenty of soap
and water. Consult a physician.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
Eye contact : In the case of contact with eyes, rinse immediately with plenty
of water and seek medical advice. Call a physician
immediately.
Ingestion : Call a physician immediately. Clean mouth with water and drink
afterwards plenty of water. Do not induce vomiting without
medical advice. Never give anything by mouth to an
unconscious person.
5. Fire-fighting measures
Suitable extinguishing : Water spray, Dry powder, Foam
media
Specific hazards during fire : Heating or fire can release toxic gas.
fighting
Special protective : In the event of fire, wear self-contained breathing apparatus.
equipment for fire-fighters
Additional advice : Use water spray to cool unopened containers.
6. Accidental release measures
Personal precautions : Use respirator when performing operations involving potential
exposure to vapour of the product.
Environmental precautions : Prevent product from entering drains.
Methods for cleaning up : Do not flush into surface water or sanitary sewer system.
Sweep up or vacuum up spillage and collect in suitable
container for disposal.
7. Handling and storage
Handling
Safe handling advice : Avoid contact with skin and eyes. Provide sufficient air
exchange and/or exhaust in work rooms.
Advice on protection : Take precautionary measures against static discharges.
against fire and explosion
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
8. Exposure controls / personal protection
Components with workplace control parameters
Glycerol (CAS-No.: 56-81-5)
US ACGIH
Exposure limit(s) : 10 mg/m3
Personal protective equipment
Hygiene measures : Wash hands before breaks and immediately after handling the
product. Avoid contact with skin, eyes and clothing.
Respiratory protection : Use respirator when performing operations involving potential
exposure to vapour of the product.
Hand protection : Wear suitable gloves.
Eye protection : Wear eye/face protection.
Skin and body protection : Wear suitable protective clothing and gloves.
9. Physical and chemical properties
Appearance
State of aggregation : liquid
Form : clear, viscous
Colour : yellow
Odour : mild
Safety data
pH : no data available
Melting point/range : no data available
Boiling point/boilingrange : no data available
Flash point : > 94 ??C
Density : no data available
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
Water solubility : soluble
10. Stability and reactivity
Conditions to avoid : no data available
Materials to avoid : Strong oxidizing agents
Hazardous reactions : Stable under normal conditions.
11. Toxicological information
The following toxicological data refer to:
Glycerol (CAS-No.: 56-81-5)
Acute oral toxicity (LD50) : > 10 000 mg/kg
Species: rat
Acute dermal toxicity : > 10 000 mg/kg
(LD50) Species: rabbit
Skin irritation : mild irritant
Species: rabbit
Exposure time: 24 h
Eye irritation : mild irritant
Species: rabbit
Genotoxicity in vitro : negative
Ames test, Salmonella typhimurium
Literary reference
negative
Chromosome aberration test in vitro, CHO cells
Literary reference
negative
Gene mutation, CHO cells
Literary reference
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
12. Ecological information
The following ecotoxicological data refer to:
Glycerol (CAS-No.: 56-81-5)
Ecotoxicity effects
Toxicity to fish (LC0) : > 10 000 mg/l
Species: Leuciscus idus (Golden orfe)
Acute toxicity
Exposure time: 48 h
Method: DIN 38412 Part 15
Toxicity to daphnia (EC50) : > 10 000 mg/l
Species: Daphnia magna (Water flea)
Immobilization
Exposure time: 24 h
Toxicity to algae (EC10) : > 10 000 mg/l
Species: Scenedesmus subspicatus
Cell multiplication inhibition test
Exposure time: 8 d
Toxicity to bacteria (EC10) : > 10 000 mg/l
Species: Pseudomonas putida
Cell multiplication inhibition test
Exposure time: 16 h
Persistence and degradability
Biodegradability : Closed Bottle test: 93 %
Readily biodegradable.
Testing period: 30 d
Method: OECD 301
13. Disposal considerations
Waste from residues : Contact waste disposal services.
Dispose of in accordance with local regulations.
Contaminated packaging : Where possible recycling is preferred to disposal or
incineration.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
14. Transport information
ADR : Not dangerous goods
RID : Not dangerous goods
IATA Cargo : Not dangerous goods
IATA Passenger : Not dangerous goods
IMDG-Code : Not dangerous goods
49 CFR : Not dangerous goods
TDG : Not dangerous goods
15. Regulatory information
Additional advice : Classification and labelling according to Directive 1999/45/EC.
Symbol(s) :
:
Harmful
R-phrase(s) R42: May cause sensitization by inhalation.
S-phrase(s) S24/25: Avoid contact with skin and eyes.
National legislation
Water contaminating class : WGK 1: slightly water endangering
(Germany)
16. Other information
Other regulations : The components of this product are reported in the following
inventories: EINECS, TSCA.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
R-phrase(s)
R36/37/38 : Irritating to eyes, respiratory system and skin.
R42 : May cause sensitization by inhalation.
Changes since the last version are highlighted in the margin. This version replaces all previous
versions.
The information provided in this Safety Data Sheet is correct to the best of our knowledge,
information and belief at the date of its publication. The information given is designed only as a
guidance for safe handling, use, processing, storage, transportation, disposal and release and is not
to be considered a warranty or quality specification. The information relates only to the specific
material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007
Natrulon HT
Version: 06.09.2007 / EN
1. Identification of the substance/preparation and of the company/undertaking
Trade name : Natrulon HT
Company : Lonza Ltd
Muenchensteinerstrasse 38
CH-4002 Basel, Switzerland
Telephone: +41 61 316 81 11
Emergency telephone : Lonza Ltd, CH-4002 Basel, Switzerland
Telephone: +41 61 313 94 94 (24h)
Contact person : prodinfo@lonza.com
2. Hazards identification
Classification
May cause sensitization by inhalation.
3. Composition/information on ingredients
Components / EC Label Concentration
Glycerol (CAS-No.: 56-81-5) (EEC-No.: 200-289-5) 47 - 50 % (*)
Papain (CAS-No.: 9001-73-4) (EEC-No.: 232-627-2) Xn; R36/37/38, 2 - 15 %
R42
Decaglycerol (CAS-No.: 9041-07-0) (EEC-No.: 232-921-0) 1- 3%
Water (CAS-No.: 7732-18-5) (EEC-No.: 231-791-2) 35 - 45 %
R-phrase(s) See chapter 16
(*) Components with workplace control parameters See chapter 8
4. First aid measures
Inhalation : Remove to fresh air. If breathing is irregular or stopped,
administer artificial respiration. If symptoms persist, call a
physician.
Skin contact : After contact with skin, wash immediately with plenty of soap
and water. Consult a physician.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
Eye contact : In the case of contact with eyes, rinse immediately with plenty
of water and seek medical advice. Call a physician
immediately.
Ingestion : Call a physician immediately. Clean mouth with water and drink
afterwards plenty of water. Do not induce vomiting without
medical advice. Never give anything by mouth to an
unconscious person.
5. Fire-fighting measures
Suitable extinguishing : Water spray, Dry powder, Foam
media
Specific hazards during fire : Heating or fire can release toxic gas.
fighting
Special protective : In the event of fire, wear self-contained breathing apparatus.
equipment for fire-fighters
Additional advice : Use water spray to cool unopened containers.
6. Accidental release measures
Personal precautions : Use respirator when performing operations involving potential
exposure to vapour of the product.
Environmental precautions : Prevent product from entering drains.
Methods for cleaning up : Do not flush into surface water or sanitary sewer system.
Sweep up or vacuum up spillage and collect in suitable
container for disposal.
7. Handling and storage
Handling
Safe handling advice : Avoid contact with skin and eyes. Provide sufficient air
exchange and/or exhaust in work rooms.
Advice on protection : Take precautionary measures against static discharges.
against fire and explosion
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
8. Exposure controls / personal protection
Components with workplace control parameters
Glycerol (CAS-No.: 56-81-5)
US ACGIH
Exposure limit(s) : 10 mg/m3
Personal protective equipment
Hygiene measures : Wash hands before breaks and immediately after handling the
product. Avoid contact with skin, eyes and clothing.
Respiratory protection : Use respirator when performing operations involving potential
exposure to vapour of the product.
Hand protection : Wear suitable gloves.
Eye protection : Wear eye/face protection.
Skin and body protection : Wear suitable protective clothing and gloves.
9. Physical and chemical properties
Appearance
State of aggregation : liquid
Form : clear, viscous
Colour : yellow
Odour : mild
Safety data
pH : no data available
Melting point/range : no data available
Boiling point/boilingrange : no data available
Flash point : > 94 ??C
Density : no data available
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
Water solubility : soluble
10. Stability and reactivity
Conditions to avoid : no data available
Materials to avoid : Strong oxidizing agents
Hazardous reactions : Stable under normal conditions.
11. Toxicological information
The following toxicological data refer to:
Glycerol (CAS-No.: 56-81-5)
Acute oral toxicity (LD50) : > 10 000 mg/kg
Species: rat
Acute dermal toxicity : > 10 000 mg/kg
(LD50) Species: rabbit
Skin irritation : mild irritant
Species: rabbit
Exposure time: 24 h
Eye irritation : mild irritant
Species: rabbit
Genotoxicity in vitro : negative
Ames test, Salmonella typhimurium
Literary reference
negative
Chromosome aberration test in vitro, CHO cells
Literary reference
negative
Gene mutation, CHO cells
Literary reference
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
12. Ecological information
The following ecotoxicological data refer to:
Glycerol (CAS-No.: 56-81-5)
Ecotoxicity effects
Toxicity to fish (LC0) : > 10 000 mg/l
Species: Leuciscus idus (Golden orfe)
Acute toxicity
Exposure time: 48 h
Method: DIN 38412 Part 15
Toxicity to daphnia (EC50) : > 10 000 mg/l
Species: Daphnia magna (Water flea)
Immobilization
Exposure time: 24 h
Toxicity to algae (EC10) : > 10 000 mg/l
Species: Scenedesmus subspicatus
Cell multiplication inhibition test
Exposure time: 8 d
Toxicity to bacteria (EC10) : > 10 000 mg/l
Species: Pseudomonas putida
Cell multiplication inhibition test
Exposure time: 16 h
Persistence and degradability
Biodegradability : Closed Bottle test: 93 %
Readily biodegradable.
Testing period: 30 d
Method: OECD 301
13. Disposal considerations
Waste from residues : Contact waste disposal services.
Dispose of in accordance with local regulations.
Contaminated packaging : Where possible recycling is preferred to disposal or
incineration.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
14. Transport information
ADR : Not dangerous goods
RID : Not dangerous goods
IATA Cargo : Not dangerous goods
IATA Passenger : Not dangerous goods
IMDG-Code : Not dangerous goods
49 CFR : Not dangerous goods
TDG : Not dangerous goods
15. Regulatory information
Additional advice : Classification and labelling according to Directive 1999/45/EC.
Symbol(s) :
:
Harmful
R-phrase(s) R42: May cause sensitization by inhalation.
S-phrase(s) S24/25: Avoid contact with skin and eyes.
National legislation
Water contaminating class : WGK 1: slightly water endangering
(Germany)
16. Other information
Other regulations : The components of this product are reported in the following
inventories: EINECS, TSCA.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007 SAFETY DATA SHEET
Natrulon HT
Version: 06.09.2007 / EN
R-phrase(s)
R36/37/38 : Irritating to eyes, respiratory system and skin.
R42 : May cause sensitization by inhalation.
Changes since the last version are highlighted in the margin. This version replaces all previous
versions.
The information provided in this Safety Data Sheet is correct to the best of our knowledge,
information and belief at the date of its publication. The information given is designed only as a
guidance for safe handling, use, processing, storage, transportation, disposal and release and is not
to be considered a warranty or quality specification. The information relates only to the specific
material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text.
172.15 / 000000005418 / 1.3 / EN / 06.09.2007
Decaglycerol
China (Mainland)] 
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Assessed
Premium
United States] 
Premium