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| CAS No.: | 9041-08-1 |
|---|---|
| Name: | Heparin, sodium salt |
| Molecular Structure: | |
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| Formula: | Unspecified |
| Molecular Weight: | 0 |
| Synonyms: | Alfa87-120;Alfa 87-163;Alfa 87-198;Alfa 87-81;Alfa 88-247;Ardeparin sodium;Badyket;Clivarin 1750;Fragmin;Fragmin IV;H 2149;Hed-Heparin;Hepaflush;Hepagumin;Hepalean;Heparin Fragment Kabi 2165;Heparin sodium;HeparineChoay;Heprinar;Hepsal;Ivor;Kabi 2165;LHN 1;Lioton1000;Lipo-Hepin;Lipo-Hepinette;Longheparin;Minihep;Monoparin;Normiflo;RO 11;Thromboliquine;Unihep;Viatromb;WY 90493RD;Zibor; |
| EINECS: | 232-681-7 |
| Density: | |
| Melting Point: | |
| Boiling Point: | |
| Flash Point: | |
| Solubility: | Soluble in water |
| Appearance: | |
| Hazard Symbols: | R36/37/38-42/43:; |
| Risk Codes: | 36/37/38-42/43 |
| Safety: | 22-24-26-36/37 |
| Transport Information: | |
| PSA: | 0.00000 |
| LogP: | 0.00000 |
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Synonyms: Ardeparin sodium ; Deligoparin sodium ; Minolteparin sodium ; Nadroparine sodium
Chemical Formula: ca. (C12H16NS2Na3)20
Molecular Weight: ca. 12000
EINECS: 232-681-7
storage temp.: 2-8°C
solubility: H2O: 50 mg/mL, clear, faintly yellow
Form of Heparin sodium(CAS NO.9041-08-1): crystalline (fine)
Appearance of Heparin sodium (CAS NO.9041-08-1): white powder
Odor: Odorless.
pH: 6.0-7.5 (1% aqueous solution)
Merck: 14,4653
| 1. | scu-wmn TDLo:3400 units/kg/17D-I:SKN | DICPBB Drug Intelligence and Clinical Pharmacy. 18 (1984),313. | ||
| 2. | scu-man TDLo:7 mg/kg/4D:CNS,SKN,BLD | JAMAAP JAMA, Journal of the American Medical Association. 244 (1980),1831. | ||
| 3. | ivn-wmn TDLo:700 units/kg/13D-I:BLD | NEJMAG New England Journal of Medicine. 303 (1980),788. | ||
| 4. | ivn-rat LD50:354 mg/kg | DEBIDR Developments in Biochemistry. 12 (1981),535. | ||
| 5. | ivn-mus LD50:2800 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 102 (1951),156. | ||
| 6. | ivn-dog LD50:1 g/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 102 (1951),156. |
Heparin sodium (CAS NO.9041-08-1) hasn't been listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
Risk Statements: 36/37/38-42/43
R36/37/38:Irritating to eyes, respiratory system and skin.
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 22-24-26-36/37
S22:Do not breathe dust.
S24:Avoid contact with skin.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
WGK Germany: 2
RTECS: MI0850000
F: 3-10
Poison by intravenous route. Human systemic effects: corrosive dermatitis, hallucinations and distorted perceptions, hemorrhage, thrombocytopenia. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also HEPARIN.
Assay of HEPARIN SODIUM: 98 - 100%
Heparin sodium (CAS NO.9041-08-1) should be kept in a tightly closed container, stored in a cool, dry, ventilated area. we should protect against physical damage.It should isolate from incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product. Heparin sodium (CAS NO.9041-08-1) is stable at room temperature in closed containers under normal storage and handling conditions, and incompatible with strong oxidizing agents, strong bases. Heparin sodium (CAS NO.9041-08-1)should avoid the condition like incompatible materials, excess heat, exposure to moist air or water. It is incompatibilities with other materials strong oxidizing agents. Its hazardous decomposition products are carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide, sodium oxide.
