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HENAN SUNLAKE ENTERPRISE CORPORATION(-)-EPOTHILONE A//file1.lookchem.com/300w/synthetic/2022-02-06-07/a084a91b-e9d1-463d-8de0-972c3099b3f9.png
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(-)-EPOTHILONE A CAS NO.152044-53-6

Min.Order Quantity:
100 Kilogram
Purity:
99%
Port:
China Main Port
Payment Terms:
L/C,D/A,D/P,T/T,Other

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Product Details

Keywords

  • (-)-EPOTHILONE A
  • 152044-53-6
  • C26H39NO6S

Quick Details

  • ProName: (-)-EPOTHILONE A
  • CasNo: 152044-53-6
  • Molecular Formula: C26H39NO6S
  • Appearance: powder
  • Application: 152044-53-6
  • DeliveryTime: Within 3-7 days
  • PackAge: Depended
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Month
  • Purity: 99%
  • Storage: Store in dry, dark and ventilated plac...
  • Transportation: by air or by sea
  • LimitNum: 100 Kilogram
  • Application: Multipurpose intermediate
  • Application: ISO/9001 Certificate

Superiority

(-)-epothilone a basic information
product name: (-)-epothilone a
synonyms: 4,17-dioxabicyclo14.1.0heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12-tetramethyl-3-(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (1s,3s,7s,10r,11s,12s,16r)-;epothilone-s;(1s,3s,7s,10r,11s,12s,16r)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione;epothile;4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione,7,11-dihydroxy-8,8,10,12-tetramethyl-3- [(1e)-1-methy;ixabepilone impurity 5 (epothilone a);(1s,3s,7s,10r,11s,12s,16r,e)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-(1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione;(1s,3s,7s,10r,11s,12s,16r)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione epothilone a
cas: 152044-53-6
mf: c26h39no6s
mw: 0
einecs:
product categories: chiral reagents;inhibitors;intermediates & fine chemicals;pharmaceuticals;sulfur & selenium compounds
mol file: 152044-53-6.mol
(-)-epothilone a structure
(-)-epothilone a chemical properties
mp 95℃
density 1.143
storage temp. 20°c
safety information
msds information
(-)-epothilone a usage and synthesis
usage the epothilones are a novel class of antineoplastic agents possessing antitubulin activity. epothilone a, b isolated from sorangium cellulosum was associated with cell cycle arrest at g2/m transition and apoptosis that was resisted with overexpression of β-tubulin and p-glycoprotein in human bladder carcinoma cell.
usage epothilone a is a microtubule inhibitor isolated from the myxobacteria, sorangium cellulosum. epothilone a acts by stabilising microtubule formation at the taxol binding site, and causes cell cycle arrest at the g2/m transition, leading to cytotoxicity. epothilone a has been investigated in clinical trials as an antitumour agent.
usage epothilone a is a microtubule inhibitor isolated from the myxobacteria, sorangium cellulosum. epothilone a acts by stabilising microtubule formation at the taxol binding site, and causes cell cycle arrest at the g2/m transition, leading to cytotoxicity. epothilone a has been investigated in clinical trials as an antitumor agent.

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