123-75-1 Tetrahydro pyrrole CAS NO.123-75-1

tetrahydro pyrrole basic information
product name: tetrahydro pyrrole
synonyms: azolidine;butylenimine;perhydroazole;perhydropyrrole;prolamine;pyrrole, tetrahydro-;pyrrolidene;pyrrolidin
cas: 123-75-1
mf: c4h9n
mw: 71.12
einecs: 204-648-7
product categories: imidazoles, pyrroles, pyrazoles, pyrrolidines;flavor;aliphatics;heterocycles;intermediates & fine chemicals;pharmaceuticals;building blocks;c4 to c8;chemical synthesis;heterocyclic building blocks;pyrrolidines
mol file: 123-75-1.mol
tetrahydro pyrrole structure
tetrahydro pyrrole chemical properties
mp -63 °c
bp 87-88 °c(lit.)
density 0.866
vapor density 2.45 (vs air)
vapor pressure 128 mm hg ( 39 °c)
fema 3523
refractive index n20/d 1.443(lit.)
fp 37 °f
storage temp. flammables area
sensitive air sensitive
merck 14,8015
brn 102395
stability: stable; flammable. incompatible with strong acids, strong oxidizing agents.
cas database reference 123-75-1(cas database reference)
nist chemistry reference pyrrolidine(123-75-1)
epa substance registry system pyrrolidine(123-75-1)
safety information
hazard codes f,t,c
risk statements 11-22-23-34-35-20/21/22-20/22-r35-r20/21/22-r11
safety statements 16-26-36/37/39-45-33-s45-s36/37/39-s26-s16
ridadr un 1922 3/pg 2
wgk germany 2
rtecs ux9650000
f 34
hazardclass 3
packinggroup ii
hazardous substances data 123-75-1(hazardous substances data)
msds information
provider language
sigmaaldrich english
acros english
alfa english
tetrahydro pyrrole usage and synthesis
chemical properties colourless to pale yellow liquid with a penetrating
usage a heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds, namely matrix metalloprotein inhibitors (mmpis) and aminopeptidase n inhibitors (apnis).
general description a colorless to pale yellow liquid with an ammonia-like odor. flash point 37°f. density 0.85 g / cm3. vapors heavier than air. produces toxic oxides of nitrogen during combustion.
air & water reactions highly flammable. very soluble in water.
reactivity profile tetrahydro pyrrole neutralizes acids in exothermic reactions to form salts plus water. may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. may generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. an explosion occurred when a mixture of tetrahydro pyrrole, benzaldehyde, and propionic acid was heated in an attempt to form porphyrins.
health hazard may cause toxic effects if inhaled or ingested/swallowed. contact with substance may cause severe burns to skin and eyes. fire will produce irritating, corrosive and/or toxic gases. vapors may cause dizziness or suffocation. runoff from fire control or dilution water may cause pollution.
fire hazard flammable/combustible material. may be ignited by heat, sparks or flames. vapors may form explosive mixtures with air. vapors may travel to source of ignition and flash back. most vapors are heavier than air. they will spread along ground and collect in low or confined areas (sewers, basements, tanks). vapor explosion hazard indoors, outdoors or in sewers. runoff to sewer may create fire or explosion hazard. containers may explode when heated. many liquids are lighter than water.
tetrahydro pyrrole preparation products and raw materials
preparation products 4-pyrrolidinobutylamine-->4,5,6,7-tetrahydro-2-methylfuro[3,2-c]pyridine-->6-bromoindole-3-carboxaldehyde-->6-methoxyindole-->ramipril-->6-methoxy-1h-indole-3-carbaldehyde-->n-[2-(4-bromophenoxy)ethyl]pyrrolidine-->bis(pinacolato)diboron -->1-benzyl-3-methyl-4-piperidone-->6-benzyloxyindole-->2-pyrrolidinoethyl chloride hydrochloride-->bepridil-->1-(4-amino-2,6-dichlorophenoxy)-3-(pyrrolidin-1-yl)propan-2-ol-->alizapride-->3,5-dimethylisoxazole-4-carbonyl chloride-->(2-pyrrolidin-1-yl-ethyl)-hydrazine-->gestrinone-->6-fluorotryptamine hydrochloride-->1-(2-aminoethyl)pyrrolidine-->simvastatin-->indole-6-carboxylic acid-->3,5-dimethylisoxazole-4-carboxylic acid-->tosufloxacin tosilate-->3-methyl-4-isoxazolecarboxylic acid-->1-(3-pyrrolidinopropyl)piperazine-->5-bromo-2-(pyrrolidin-1-yl)pyrimidine-->ethyl 3,5-dimethylisoxazole-4-carboxylate-->methyl 3-((pyrrolidin-1-yl)methyl)benzoate-->[6-(1-pyrrolidinyl)-3-pyridinyl]methanol-->4-(1-pyrrolidinyl)piperidine-->6-(1-pyrrolidinyl)nicotinaldehyde-->6-(1-pyrrolidinyl)-3-pyridinamine-->barnidipine-->pyrrolidin-1-yl-acetic acid-->rocuronium bromide-->pyrrolidine-1-sulfonyl chloride-->1-ethoxycarbonyl-3-pyrrolidione-->5-nitro-2-(1-pyrrolidinyl)pyridine-->5-bromo-2-(pyrrolidin-1-yl)pyridine-->sultopride hydrochloride

our company was built in 2009 with an iso certificate.in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.our main business covers the fields below:

1.noble metal catalysts (pt.pd...)

2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)

3.oled intermediates (fluorene,carbazole,boric acid...)

4.customs synthesis

our advantage:

1. higest quality and good package

2.fast delivery

3.better payment term

4.fast response to customer within 6 hours

5.good business credit in europe ,us ,japan ,korea

anyway ,if you need any chemicals from china ,henan tianfu can help you