4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid CAS NO.149709-62-6

Min.Order Quantity:: 100 Metric Ton

Purity:: 98%min

Port:: Qingdao,China

Payment Terms:: L/C,T/T,MoneyGram,Other

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149709-62-6
Sell high quality 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid
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ProName: 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5...
CasNo: 149709-62-6
Molecular Formula: C24H29NO5
Appearance: white powder
Application: Used for research and industrial manuf...
DeliveryTime: Within7-10 days after receipt of your ...
PackAge: As customer request
Port: Qingdao,China
ProductionCapacity: 100kg/Month Metric Ton/Day
Purity: 98%min
Storage: Store in a cool,dry place and keep awa...
Transportation: Common products:Sea/Air/Courier Dange...
LimitNum: 100 Metric Ton

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hp90699 ahu-377 (sacubitril) 149709-62-6

ahu-377 (sacubitril) 149709-62-6

mf c24h29no5 c4h11no3

msds:aviable

mw 532.6

place of origin:china

synonym: sacubitril

ahu-377 (sacubitril) description

ahu-377 (sacubitril) is a prodrug which is activated in vivo by hydrolytic enzyme esterases to form an active compound lbq657 that selectively and potently inhibits the enzyme neprilysin with ki at low nm. neprilysin is a protease responsible for the degradation of atrial and brain natriuretic peptides. inhibition of the enzyme prevents the degradation of natriuretic peptides and activates cgmp signaling pathways that regulate volume and blood pressure. ahu-377 (sacubitril) is an investigational antihypertensive drug being studied for use in combination with valsartan (molar ratio: 1:1) (our prod no. ct-vals). the combination drug, known as lcz696, is in clinical trials for the treatment of heart failure.

ahu-377 (sacubitril) structual