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HENAN SUNLAKE ENTERPRISE CORPORATIONAmlodipine besilate//file1.lookchem.com/cas/reactions/2021/05/26/8378713.png
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Amlodipine besilate CAS NO.111470-99-6

Min.Order Quantity:
1 Kilogram
Purity:
98%
Port:
shanghai port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • 2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE
  • 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate
  • AMLODIPINE BENZENESULFONATE

Quick Details

  • ProName: Amlodipine besilate
  • CasNo: 111470-99-6
  • Molecular Formula: C26H31ClN2O8S
  • Appearance: White Crystalline Solid
  • Application: Amlodipine besylate is a L-type calciu...
  • DeliveryTime: within 3-7 days
  • PackAge: depended
  • Port: shanghai port
  • ProductionCapacity: 200 Kilogram/Month
  • Purity: 98%
  • Storage: Store in dry, dark and ventilated plac...
  • Transportation: by air or by sea
  • LimitNum: 1 Kilogram

Superiority


preview
cbnumber: cb4127875
chemical name: amlodipine besilate
molecular formula: c26h31cln2o8s
formula weight: 567.05
cas no.: 111470-99-6

Details

amlodipine besilate basic information
product name: amlodipine besilate
synonyms: 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate;amlodipine benzenesulfonate;amlodipine besilate;amlodipine besylate;norvasc;3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,;4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
cas: 111470-99-6
mf: c26h31cln2o8s
mw: 567.05
einecs:
product categories: active pharmaceutical ingredients;dihydropyridine class chemicals;intermediates & fine chemicals;pharmaceuticals;amlodipine;aromatics;dihydropyridine;heterocycles;benicar;azd929;fine chemical
mol file: 111470-99-6.mol
amlodipine besilate structure
amlodipine besilate chemical properties
mp 199-201°c
storage temp. store at rt
solubility dmso: 20 mg/ml
form solid
color white
cas database reference 111470-99-6(cas database reference)
safety information
hazard codes xn
risk statements 22-36/37/38-20/21/22
safety statements 26-36
wgk germany 3
rtecs us7967700
hazardous substances data 111470-99-6(hazardous substances data)

amlodipine besilate usage and synthesis
chemical properties white crystalline solid
usage a dihydropyridine calcium channel blocker. used as an antianginal and antihypertensive
usage angiotensin ii inhibitor prodrug, antihypertensive
usage amlodipine besylate is a l-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. amlodipine also inhibits growth of human epidermoid carcinoma a431 cells and has antireproductive effects in male rats.
biological activity l-type calcium channel blocker that displays antihypertensive properties. inhibits ca 2+ -induced contractions in depolarized rat aorta (ic 50 = 1.9 nm) and displays vasoprotective effects in cardiovascular disease. inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma a431 cells (ic 50 = 25 μ m).

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