Buy High quality /lowest price Calcipotriol CAS NO.112965-21-6

Min.Order Quantity:: 1 Gram

Purity:: 99%

Port:: any port in China

Payment Terms:: L/C,D/A,D/P,T/T

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ProName: Buy High quality /lowest price Calcipo...
CasNo: 112965-21-6
Molecular Formula: C39H68O3Si2
Appearance: White powder
Application: Protected trans-Calcipotriol, a vitami...
DeliveryTime: 3-5 days after confirmation
PackAge: According to your demand
Port: any port in China
ProductionCapacity: 100 Kilogram/Week
Purity: 99%
Storage: under nitrogen -18 degree celisus
Transportation: as requested
LimitNum: 1 Gram
Grade: Pharma Grade

Superiority

buy high quality /lowest price calcipotriol

calcipotriol increased hcap18 mrna expression in il-17/il-22-stimulated keratinocytes. however, ll37 peptide in the culture supernatants was reduced by calcipotriol. calcipotriol and fty720 augment il-2-activated nk cell lysis of k562 and raji tumor cell lines as well as immature (i) and mature (m) dcs, with variable efficacies. vitamin d3, calcipotriol and fty720 enhance nk17/nk1 cell lysis of k562 cells, suggesting that a possible mechanism of action for these drugs is via activating these newly described cells. mc903 (calcipotriol) is a novel vitamin d3 analogue which is at least 100 times less potent than 1,25-(oh)-2-d3 in its effects on calcium homeostasis.

name

calcipotriene

synonyms

(1s,3s,5z)-5-[(2e)-2-[(1r,3ar,7ar)-1-[(e,2s)-5-cyclopropyl-5-hydroxy-pent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol

molecular structure

112965 21 6 - calcipotriene cas 112965-21-6

molecular formula

c27h40o3

molecular weight

412.61

cas number(or watson number for non-cas products)

112965-21-6

einecs

assay, purity or standard

98% min

identification

hnmr/ir

Details

calcipotriol (inn) or calcipotriene (usan) is a synthetic derivative of calcitriol or vitamin d. it is used in the treatment of psoriasis, marketed under the trade name "dovonex" in the united states, "daivonex" outside of north america, and "psorcutan" in germany. this medication is safe for long-term application in psoriatic skin condition.

product name	calcipotriol
cas no.	112965-21-6
molecular formula	c27h40o3	molecular weight	412.61
batch no.	140101	mfg. date	jan.10,2014
quantity	15g	retest. date	jan.9,2016

items	specifications			results
appearance	white or almost white crystalline powder			conforms
identification	a) ir	ir chromatograph conforms to the characteristic peak of r.s.		conforms
	b) hplc	the retention time of the major peak in the chromatogram conforms to the characteristic peak of r.s.		conforms
related substances	known impurity	impurity c((5e)-calcipotriol)	nmt1.0%	0.60%
		impurity d (24-epi-calcipotriol)	nmt1.0%	0.40%
		impurity i (suprasterol of calcipotriol)	nmt0.10%	nd
	any other impurity		nmt 0.1%	0.09%
	total impurities		nmt2.5%	1.3%
heavy metals	<20ppm			conforms
lod	not more than 1.0%			0.4%
solvent residue	acetone≤0.5%			0.1%
assay	95.5~102.0%			98.9%