USD $6.00-9.00 / Gram
USD $5.00-10.00 / Gram
USD $6.00-9.00 / Gram
USD $6.00-9.00 / Gram
USD $5.00-10.00 / Gram
USD $6.00-9.00 / Gram
USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
mainly used for anti - inflammatory and anti - allergic, for rheumatoid arthritis and other collagen diseases, etc.
16alpha)-;16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-(11bet;16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-2,20-dione;16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2;16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione;16-alpha-methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-dien;16alpha-methyl-9alpha-fluoro-11beta-17alpha-21-trihydroxypregna-1,4-diene-3,20-dione;16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol
mp | 262-264 °c(lit.) |
alpha | 75 º (c=1, dioxane) |
refractive index | 76 ° (c=1, dioxane) |
storage temp. | 2-8°c |
solubility | ethanol: 1 mg/ml |
form | powder |
color | off-white |
water solubility | 10 mg/100 ml (25 ºc) |
merck | 14,2943 |
brn | 2066651 |
stability: | stable. combustible. incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. may be light sensitive. |
cas database reference | 50-02-2(cas database reference) |
nist chemistry reference | prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2) |
epa substance registry system | pregna-1,4-diene- 3,20-dione, 9-fluoro-11,17,21-trihydroxy- 16-methyl-, (11.beta.,16.alpha.)-(50-02-2) |
hazard codes | xi,xn,t,f |
risk statements | 43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11 |
safety statements | 36/37-45-36-26-22-16 |
wgk germany | 2 |
rtecs | tu3980000 |
hazardous substances data | 50-02-2(hazardous substances data) |
chemical properties | white crystalline solid |
usage | a glucocorticoid anti-inflammatory agent. regulates t cell survival, growth, and differentiation. inhibits the induction of nitric oxide synthase |
usage | dexamethasone is a glucocorticoid used as an anti-inflammatory agent. dexamethasone regulates t cell survival, growth, and differentiation. dexamethasone inhibits the induction of nitric oxide synthas e. |
general description | odorless white to off-white crystalline powder with a slightly bitter taste. |
air & water reactions | insoluble in water. |
reactivity profile | dexamethasone may be sensitive to prolonged exposure to light. dexamethasone is incompatible with strong oxidizers, strong acids, acid chlorides and acid anhydrides. oxidation may occur with bases. |
fire hazard | flash point data for dexamethasone are not available; however, dexamethasone is probably combustible. |
biological activity | glucocorticoid; anti-inflammatory. reduces levels of activated nf- κ b in immature dendritic cells (dcs) and inhibits differentiation into mature dcs. |