USD $100.00-150.00 / Metric Ton
entecavir , entecavir,
entecavir abbreviated etv, is an oral antiviral drugused in the treatment of hepatitis b infection. it is marketed under the trade names baraclude (bms) and entaliv (drl).
entecavir , entecavir,
entecavir abbreviated etv, is an oral antiviral drugused in the treatment of hepatitis b infection. it is marketed under the trade names baraclude (bms) and entaliv (drl).
entecavir , entecavir,
entecavir abbreviated etv, is an oral antiviral drugused in the treatment of hepatitis b infection. it is marketed under the trade names baraclude (bms) and entaliv (drl).
entecavir is a nucleoside analog[1] (more specifically, a guanosineanalogue) that inhibits reverse transcription, dna replication andtranscription in the viral replication process. the drug's manufacturer claims that entecavir is more efficacious than previous agents used to treat hepatitis b (lamivudine and adefovir).
systematic (iupac) name | |
---|---|
2-amino-9-[(1s,3r,4s)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-6,9-dihydro-3h-purin-6-one | |
clinical data | |
trade names | baraclude |
ahfs/drugs.com | monograph |
medlineplus | a605028 |
licence data | ema:link, us fda:link |
pregnancy cat. | c (us) |
legal status | -only (us) |
routes | oral |
pharmacokinetic data | |
protein binding | 13% |
half-life | 128–149 hours |
excretion | renal 62–73% |
identifiers | |
cas number | 142217-69-4 |
atc code | j05af10 |
pubchem | cid 153941 |
drugbank | db00442 |
chemspider | 135679 |
unii | nnu2o4609d |
kegg | d04008 |
chebi | chebi:59902 |
chembl | chembl713 |
chemical data | |
formula | c12h15n5o3 |
mol. mass | 277.279 g/mol |