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HENAN SUNLAKE ENTERPRISE CORPORATIONGDC-0068//file1.lookchem.com/300w\2017-5\37f8d027-08c1-49c0-95ff-a40fe33c8620.gif
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GDC-0068 CAS NO.1001264-89-6

Min.Order Quantity:
100 Kilogram
Purity:
99%
Port:
China Main Port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • GDC-0068
  • 1001264-89-6
  • C24H32ClN5O2

Quick Details

  • ProName: GDC-0068
  • CasNo: 1001264-89-6
  • Molecular Formula: C24H32ClN5O2
  • Appearance: powder
  • Application: 1001264-89-6
  • DeliveryTime: Within 3-7 days
  • PackAge: Depended
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Month
  • Purity: 99%
  • Storage: Store in dry, dark and ventilated plac...
  • Transportation: by air or by sea
  • LimitNum: 100 Kilogram
  • Valid Period: 6 month
  • Application: Multipurpose intermediate
  • Application: ISO/9001 Certificate

Superiority

gdc-0068 basic information
product name: gdc-0068
synonyms: gdc-0068;gdc-0068(rg7440);rg7440;(2s)-2-(4-chlorophenyl)-1-[4-[(5r,7r)-6,7-dihydro-7-hydroxy-5-methyl-5h-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone;ipatasertib (gdc-0068);ipatasertib;(s)-2-(4-chlorophenyl)-1-(4-((5r,7r)-7-hydroxy-5-methyl-6,7-dihydro-5h-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one;(2s)-2-(4-chlorophenyl)-1-[4-[(5r,7r)-6,7-dihydro-7-hydroxy-5-methyl-5h-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone ipatasertib (gdc-0068)
cas: 1001264-89-6
mf: c24h32cln5o2
mw: 457.99618
einecs:
product categories: inhibitor;pi3k/akt/mtor;inhibitors
mol file: 1001264-89-6.mol
gdc-0068 structure
gdc-0068 chemical properties
density 1.254
safety information
msds information
gdc-0068 usage and synthesis
usage dc-0068 is a highly selective pan-akt inhibitor targeting akt1, akt2, and akt3 with ic50 of 5 nm, 18 nm, and 8 nm, respectively.
usage (2s)-2-(4-chlorophenyl)-1-[4-[(5r,7r)-6,7-dihydro-7-hydroxy-5-methyl-5h-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone is a highly selective akt inhibitor targeting akt1 , akt2 and akt3. studies have shown its use in combination with vemurafenib (v118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.

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