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HENAN SUNLAKE ENTERPRISE CORPORATIONMITHRAMYCIN A//file1.lookchem.com/300w/substances/2022-04-09-03/660fb0f0-52e4-4015-92e4-165f65e4d2b8.png
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MITHRAMYCIN A CAS NO.18378-89-7

Min.Order Quantity:
1 Kilogram
Purity:
90%
Port:
China Main Port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • MITHRAMYCIN A
  • 18378-89-7
  • C52H76O24

Quick Details

  • ProName: MITHRAMYCIN A
  • CasNo: 18378-89-7
  • Molecular Formula: C52H76O24
  • Appearance: yellow powder
  • Application: 18378-89-7
  • DeliveryTime: Within 3-7days
  • PackAge: As requested
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Day
  • Purity: 90%
  • Storage: 2-8°C
  • Transportation: By air or by sea
  • LimitNum: 1 Kilogram

Superiority

mithramycin a basic information
product name: mithramycin a
synonyms: aureolic acid;methramycin a;mithracin;mithramycin;mithramycin a;mithramycin a, streptomyces plicatus;plicamycin;(2s-alpha,3beta(1r*,3r*4s*)))-droxy-7-methyl
cas: 18378-89-7
mf: c52h76o24
mw: 1085.15
einecs: 232-455-8
product categories: antibiotics;antitumour;antibiotic
mol file: 18378-89-7.mol
mithramycin a structure
mithramycin a chemical properties
melting point 180-183 °c
storage temp. 2-8°c
merck 13,7619
safety information
hazard codes xn,t+
risk statements 22-26/27/28
safety statements 45-38-36/37/39-28a-22
ridadr 3249
wgk germany 3
rtecs pz2800000
f 10
hazardclass 6.1(b)
packinggroup iii
mithramycin a usage and synthesis
chemical properties yellow powder
usage transcription inhibitor
usage mithramycin was the first of the aureolic acid class of antitumour antibiotics, isolated from streptomyces. mithramycin inhibits transcription and protein synthesis by non-covalent binding with g-c-rich duplex dna in the presence of magnesium and zinc ions. mithramycin also induces differentiation of leukemic cells accompanied by an early decrease in c-myc expression, and selectively inhibits collagen-1 gene expression in human fibroblasts.
usage mithramycin a was the first of the aureolic acid class of antitumor antibiotics, isolated from streptomyces. mithramycin inhibits transcription and protein synthesis by non-covalent binding with g-c-rich duplex dna in the presence of magnesium and zinc ions. mithramycin also induces differentiation of leukemic cells accompanied by an early decrease in c-myc expression, and selectively inhibits collagen-1 gene expression in human fibroblasts.
biological activity anticancer antibiotic that selectively binds to g-c-rich dna in the presence of mg 2+ or zn 2+ , inhibiting rna and dna polymerase action. inhibits c-myc expression and induces myeloid differentiation of hl-60 promyelocytic leukemia cells.

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