HENAN SUNLAKE ENTERPRISE CORPORATION
- Country:
China (Mainland) - Year Established: 2006
- Business type: Trading Company
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MITHRAMYCIN A CAS NO.18378-89-7
- Min.Order Quantity:
- 1 Kilogram
- Purity:
- 90%
- Port:
- China Main Port
- Payment Terms:
- L/C,D/A,D/P,T/T,Other
Keywords
- MITHRAMYCIN A
- 18378-89-7
- C52H76O24
Quick Details
- ProName: MITHRAMYCIN A
- CasNo: 18378-89-7
- Molecular Formula: C52H76O24
- Appearance: yellow powder
- Application: 18378-89-7
- DeliveryTime: Within 3-7days
- PackAge: As requested
- Port: China Main Port
- ProductionCapacity: 300 Kilogram/Day
- Purity: 90%
- Storage: 2-8°C
- Transportation: By air or by sea
- LimitNum: 1 Kilogram
Superiority
| mithramycin a basic information |
| product name: | mithramycin a |
| synonyms: | aureolic acid;methramycin a;mithracin;mithramycin;mithramycin a;mithramycin a, streptomyces plicatus;plicamycin;(2s-alpha,3beta(1r*,3r*4s*)))-droxy-7-methyl |
| cas: | 18378-89-7 |
| mf: | c52h76o24 |
| mw: | 1085.15 |
| einecs: | 232-455-8 |
| product categories: | antibiotics;antitumour;antibiotic |
| mol file: | 18378-89-7.mol |
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| mithramycin a chemical properties |
| melting point | 180-183 °c |
| storage temp. | 2-8°c |
| merck | 13,7619 |
| safety information |
| hazard codes | xn,t+ |
| risk statements | 22-26/27/28 |
| safety statements | 45-38-36/37/39-28a-22 |
| ridadr | 3249 |
| wgk germany | 3 |
| rtecs | pz2800000 |
| f | 10 |
| hazardclass | 6.1(b) |
| packinggroup | iii |
| mithramycin a usage and synthesis |
| chemical properties | yellow powder |
| usage | transcription inhibitor |
| usage | mithramycin was the first of the aureolic acid class of antitumour antibiotics, isolated from streptomyces. mithramycin inhibits transcription and protein synthesis by non-covalent binding with g-c-rich duplex dna in the presence of magnesium and zinc ions. mithramycin also induces differentiation of leukemic cells accompanied by an early decrease in c-myc expression, and selectively inhibits collagen-1 gene expression in human fibroblasts. |
| usage | mithramycin a was the first of the aureolic acid class of antitumor antibiotics, isolated from streptomyces. mithramycin inhibits transcription and protein synthesis by non-covalent binding with g-c-rich duplex dna in the presence of magnesium and zinc ions. mithramycin also induces differentiation of leukemic cells accompanied by an early decrease in c-myc expression, and selectively inhibits collagen-1 gene expression in human fibroblasts. |
| biological activity | anticancer antibiotic that selectively binds to g-c-rich dna in the presence of mg 2+ or zn 2+ , inhibiting rna and dna polymerase action. inhibits c-myc expression and induces myeloid differentiation of hl-60 promyelocytic leukemia cells. |
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