Mupirocin CAS NO.12650-69-0

product information

pseudomonas a. mainly through reversibly combined with isoleucine transfer rna synthetase, this product can prevent the isoleucine incorporation and terminate the protein synthesis in cells containing isoleucine, leading to bacterial death. at low concentrations, this product has the inhibitory effect and at high concentrations, it has the bactericidal effect. this product is highly sensitive to a variety of gram-positive bacteria associated with skin infections, particularly staphylococcus aureus (including drug-resistant staphylococcus aureus) and streptococcus pyogenes; and it is also available for listeria monocytogenes and erythema erysipelothrix bacteria; it is generally not sensitive to gram-negative bacteria, but have some antibacterial effect on some gram-negative bacteria such as e. coli, neisseria, haemophilus influenzae and neisseria gonorrhoeae and is not sensitive to the majority of anaerobic bacteria and the normal flora of the skin and has low efficacy against fungi.

basic information

topical antibiotics adverse reactions precautions chemical properties application production methods

product name:	mupirocin
synonyms:	mupirocin;mupirocin calcium;pseudomonic acid;pseudomonic acid a;(2s-(2-alpha(e;4-beta,5-alpha(2r*,3r*(1r*,2r*))))-3-beta;bactroban;nonanoicacid,9((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1
cas:	12650-69-0
mf:	c26h44o9
mw:	500.62
einecs:	231-791-2
product categories:	active pharmaceutical ingredients;intermediates & fine chemicals;pharmaceuticals;chiral reagents;heterocycles;api;inhibitors
mol file:	12650-69-0.mol

chemical properties

mp	77-780c
storage temp.	-20°c freezer, under inert atmosphere
solubility	h2o: 12 mg/ml, soluble
form	solid
cas database reference	12650-69-0(cas database reference)

usage and synthesis

topical antibiotics. this product is generally used for the inflammation of the skin, eczema, etc., or made into mupirocin ointment in the market.by reversibly binding to isoleucine transfer rna synthetase, this product can prevent isoleucine incorporated so that the synthesis of all proteins in cells containing isoleucine can be stopped.

pseudomonic acid is a potent antibiotic produced by pseudomonas fluorescens, reported by fuller et al. in 1971. pseudomonic acid has broad spectrum activity against gram positive bacteria and was approved for topical human use in 1985. pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-trna synthetase.

company information

henan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.

we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.

we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.