pristinamycin basic information |
product name: | pristinamycin |
synonyms: | pristinamycin;virginiamycin;antibioticno.899;eskalin500;eskalinv;mikamycin;ostreogrycin;patricin |
cas: | 11006-76-1 |
mf: | c71h84n10o17 |
mw: | 1349.48346 |
einecs: | 234-244-6 |
product categories: | intermediates & fine chemicals;pharmaceuticals |
mol file: | 11006-76-1.mol |
pristinamycin chemical properties |
mp | 170-178℃ |
safety information |
pristinamycin usage and synthesis |
usage | an antibiotic used in livestock feed to prevent disease among young swine. also is used in ethanol production to prevent microbial contamination. |
usage | virginiamycin complex is defined as a mixture of 75% ostreogrycin a (virginiamycin m1) and 25% virginiamycin s1, together with the less abundant s analogues. as the two major components have quite different solubilities, these proportions are not readily achieved or used. bioaustralis has isolated and re-combined the individual components to provide the defined components of virginiamycin complex. the composition of the complex is important as virginiamycin s1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50s ribosome induced by ostreogrycin a. |
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