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Wuhan Disel Biotechnology Co., Ltd.(expird)Pharmaceutical Peptide Bremelanotide PT-141 CAS 32780-32-8//file1.lookchem.com/cas/reactions/2021/06/25/2205586.png
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Pharmaceutical Peptide Bremelanotide PT-141 CAS 32780-32-8 CAS NO.32780-32-8

Min.Order Quantity:
10 Gram
Purity:
97%+, powder
Port:
Shanghai
Payment Terms:
T/T,Other

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Product Details

Keywords

  • Bremelanotide
  • PT-141
  • 32780-32-8

Quick Details

  • ProName: Pharmaceutical Peptide Bremelanotide P...
  • CasNo: 32780-32-8
  • Molecular Formula:
  • Appearance: white powder
  • Application:
  • DeliveryTime: 1-3 days
  • PackAge: Aluminum Foil Bag, Drum or Tin
  • Port: Shanghai
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 97%+, powder
  • Storage: Dry and cool place
  • Transportation: express, air, sea
  • LimitNum: 10 Gram
  • Trademark: Diselbiotech
  • Alias: PT-141
  • Shipping Method: DHL, FEDEX, HKEMS etc.
  • Payment Method: T/T, Western Union, MoneyGram, Paypal,...
  • Shipping Time: Send out within 24 hours after payment
  • Package: Discreet Package & Safe Shipping
  • Origin: China

Superiority

1) rich experience

we specialize in this field for many years,our pharmaceutical raw materials exported to overseas, to
europe,africa,asia, americas and other country, and we have got very good feedback from our customers
,and established long friendly relations of cooperation.


2) great quality, purity and favorable


good quality is one of our secret success, welcome order the samples.


3) safest and fastest delivery

we have adequate stock,and can arranged within 24 hours when receive the payment.tracking number
would be informed quickly after shipment.

we have special way could ship 2kg to 20tons products a time. we offer melting powder into liquid service
.and ship the liquid in special bottles.


4) good after-sales service

tell the package update asap, and will try best solve when customer encountered various problems!

everything is for customers

our products and services will focus on the largest customer demand, we hold the greatest enthusiasm
and sincere cooperation with each customer.

all in all, high quality, best service, security shipping and competitive price are our perpetual pursuance.

Details

quick details:

cas no.: 32780-32-8 other names: pt 141 mf: c7h15no4
einecs no.: 258279-04-8 place of origin: china (mainland) type: auxiliaries and other medicinal chemicals
grade standard: medicine grade usage: animal pharmaceuticals, bodybuilding
model number: purity: 99%min product name: pt141
appearance: powder grade: medical standard: usp grade
colour: white export markets: global production capacity: 10000g



pt-141 (bremelanotide) is a highly potent synthetic peptide analogue of α-msh that may elicit aphrodisiac effects through stimulation of melanocortin receptors. pt-141 (bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-melanocyte-stimulating hormone (α-msh), a multifunctional peptide that regulates a broad array of physiological functions. in studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

specification:

name: pt-141
synonyms: bremelanotide, pt-141 acetate
cas #: 189691-06-3
molecular formula: c50h68n14o10
molecular mass: 1025.2 da (g/mol)
amino acid sequence: ac-nle-cyclo[asp-his-d-phe-arg-trp-lys]-oh

function & usage:

bremelanotide, similarly to its analogues α-msh and melanotan ii, acts as a non-selective agonist of all of the melanocortin receptors except mc2, where it lacks significant affinity. reported activity of the drug is as follows:
mc1 (ki = 0.68 nm)
mc2 (ki > 1000 nm)
mc3 (ki = 72.07 nm)
mc4 (ki = 19.25 nm)
mc5 (ki = 166.8 nm)

bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the mc4 receptor (the mc3 receptor may also be involved). it modulates inflammation and limits ischemia via activation of the mc1 and mc4 receptors.

according to palatin technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan ii as an inducer of erection in male rats. in addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan ii was only 3- to 4-fold. they concluded that bremelanotide would be more tolerable than melanotan ii.

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