USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $3.00-10.00 / Kilogram
USD $3.00-10.00 / Kilogram
USD $3.00-10.00 / Kilogram
USD $11,000.00-12,000.00 / Metric Ton
USD $11,000.00-12,000.00 / Metric Ton
product name | loxo-292 selpercatinib |
selpercatinib chemical properties |
chemical name: 6-(2-hydroxy-2-methylpropoxy)-4-(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile |
cas #: 2152628-33-4 | |
chemical structure: | |
appearance: white powder
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other names: loxo-292, selpercatinib |
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what is loratadine |
selpercatinib is a kinase inhibitor with enhanced specificity for ret tyrosine kinase receptors (rtks) over other rtk classes. enhanced ret (rearranged during transfection) oncogene expression is a hallmark of many cancers. although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in ret-driven cancers, their lack of specificity is generally associated with substantial toxicity. selpercatinib (loxo-292) and pralsetinib (blu-667) represent the first generation of specific ret rtk inhibitors for the treatment of ret-driven cancers. |
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